Acute Pericarditis Questions & Answers

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3. [Guideline] Adler Y, Charron P, Imazio M, et al, for the ESC Scientific Document Group . 2015 ESC Guidelines for the diagnosis and management of pericardial diseases: The Task Force for the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology (ESC). Endorsed by: The European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2015 Nov 7. 36 (42):2921-64. [QxMD MEDLINE Link]. [Full Text].

4. Bach DS. 2015 ESC guidelines for pericardial disease. American College of Cardiology. Available at https://www.acc.org/latest-in-cardiology/ten-points-to-remember/2015/10/30/12/01/2015-esc-guidelines-for-the-diagnosis-and-management-of-pericardial-diseases. October 30, 2015; Accessed: April 2, 2019.

5. Bhardwaj R, Berzingi C, Miller C, et al. Differential diagnosis of acute pericarditis from normal variant early repolarization and left ventricular hypertrophy with early repolarization: an electrocardiographic study. Am J Med Sci. 2013 Jan. 345 (1):28-32. [QxMD MEDLINE Link].

6. Bonaventura A, Montecucco F. Inflammation and pericarditis: Are neutrophils actors behind the scenes?. J Cell Physiol. 2019 May. 234 (5):5390-8. [QxMD MEDLINE Link].

7. Blank N, Lorenz HM. Idiopathic pericarditis-an autoinflammatory disease?. Curr Rheumatol Rep. 2019 Mar 9. 21 (5):18. [QxMD MEDLINE Link].

8. Abdel-Haq N, Moussa Z, Farhat MH, Chandrasekar L, Asmar BI. Infectious and noninfectious acute pericarditis in children: an 11-year experience. Int J Pediatr. 2018. 2018:5450697. [QxMD MEDLINE Link]. [Full Text].

9. Imazio M, Brucato A, Maestroni S, et al. Risk of constrictive pericarditis after acute pericarditis. Circulation. 2011 Sep 13. 124 (11):1270-5. [QxMD MEDLINE Link].

10. Chraibi S, Ibnabdeljalil H, Habbal R, Bennis A, Tahiri A, Chraibi N. Pericardial tamponade as the first manifestation of dermatopolymyositis. Ann Med Interne (Paris). 1998 Nov. 149 (7):464-6. [QxMD MEDLINE Link].

11. Soler-Soler J, Permanyer-Miralda G, Sagrista-Sauleda J. A systematic diagnostic approach to primary acute pericardial disease. The Barcelona experience. Cardiol Clin. 1990 Nov. 8 (4):609-20. [QxMD MEDLINE Link].

12. Friman G, Fohlman J. The epidemiology of viral heart disease. Scand J Infect Dis Suppl. 1993. 88:7-10. [QxMD MEDLINE Link].

13. Silva-Cardoso J, Moura B, Martins L, Mota-Miranda A, Rocha-Goncalves F, Lecour H. Pericardial involvement in human immunodeficiency virus infection. Chest. 1999 Feb. 115 (2):418-22. [QxMD MEDLINE Link].

14. Feinstein Y, Falup-Pecurariu O, Mitrica M, et al. Acute pericarditis caused by Streptococcus pneumoniae in young infants and children: three case reports and a literature review. Int J Infect Dis. 2010 Feb. 14 (2):e175-8. [QxMD MEDLINE Link].

15. Mastroianni A, Coronado O, Chiodo F. Tuberculous pericarditis and AIDS: case reports and review. Eur J Epidemiol. 1997 Oct. 13 (7):755-9. [QxMD MEDLINE Link].

16. Lamas ES, Bononi RJR, Bernardes MVAA, et al. Acute purulent pericarditis due co-infection with Staphylococcus aureus and Mycobacterium tuberculosis as first manifestation of HIV infection. Oxf Med Case Reports. 2019 Feb. 2019 (2):omy127. [QxMD MEDLINE Link]. [Full Text].

17. Tseng JR, Lee MJ, Yen KC, et al. Course and outcome of dialysis pericarditis in diabetic patients treated with maintenance hemodialysis. Kidney Blood Press Res. 2009. 32 (1):17-23. [QxMD MEDLINE Link].

18. Imazio M, Negro A, Belli R, et al. Frequency and prognostic significance of pericarditis following acute myocardial infarction treated by primary percutaneous coronary intervention. Am J Cardiol. 2009 Jun 1. 103 (11):1525-9. [QxMD MEDLINE Link].

19. Salisbury AC, Olalla-Gomez C, Rihal CS, et al. Frequency and predictors of urgent coronary angiography in patients with acute pericarditis. Mayo Clin Proc. 2009. 84 (1):11-5. [QxMD MEDLINE Link]. [Full Text].

20. Eckart RE, Love SS, Atwood JE, et al, for the Department of Defense Smallpox Vaccination Clinical Evaluation Team. Incidence and follow-up of inflammatory cardiac complications after smallpox vaccination. J Am Coll Cardiol. 2004 Jul 7. 44 (1):201-5. [QxMD MEDLINE Link].

21. Lin AH, Phan HA, Barthel RV, et al. Myopericarditis and pericarditis in the deployed military member: a retrospective series. Mil Med. 2013 Jan. 178 (1):18-20. [QxMD MEDLINE Link].

22. Murthy SC, Rozas MS, Adelstein DJ, et al. Induction chemoradiotherapy increases pleural and pericardial complications after esophagectomy for cancer. J Thorac Oncol. 2009 Mar. 4 (3):395-403. [QxMD MEDLINE Link].

23. Lorell BH. Pericardial diseases. In: Braunwald E, ed. Heart Disease: A Textbook of Cardiovascular Medicine. 5th ed. Philadelphia, Pa: WB Saunders; 1997. 1478-534.

24. Brady WJ, Perron AD, Martin ML, Beagle C, Aufderheide TP. Cause of ST segment abnormality in ED chest pain patients. Am J Emerg Med. 2001 Jan. 19 (1):25-8. [QxMD MEDLINE Link].

25. Merce J, Sagrista Sauleda J, Permanyer Miralda G, Carballo J, Olona M, Soler Soler J. [Pericardial effusion in the elderly: A different disease?] [Spanish]. Rev Esp Cardiol. 2000 Nov. 53 (11):1432-6. [QxMD MEDLINE Link].

26. Sagrista-Sauleda J, Barrabes JA, Permanyer-Miralda G, Soler-Soler J. Purulent pericarditis: review of a 20-year experience in a general hospital. J Am Coll Cardiol. 1993 Nov 15. 22 (6):1661-5. [QxMD MEDLINE Link].

27. Imazio M, Brucato A, Adler Y, et al. Prognosis of idiopathic recurrent pericarditis as determined from previously published reports. Am J Cardiol. 2007 Sep 15. 100 (6):1026-8. [QxMD MEDLINE Link].

28. Cremer PC, Kumar A, Kontzias A, et al. Complicated pericarditis: understanding risk factors and pathophysiology to inform imaging and treatment. J Am Coll Cardiol. 2016 Nov 29. 68 (21):2311-28. [QxMD MEDLINE Link].

29. Estok L, Wallach F. Cardiac tamponade in a patient with AIDS: a review of pericardial disease in patients with HIV infection. Mt Sinai J Med. 1998 Jan. 65 (1):33-9. [QxMD MEDLINE Link].

30. Lazaros G, Antonopoulos AS, Imazio M, et al. Clinical significance of pleural effusions and association with outcome in patients hospitalized with a first episode of acute pericarditis. Intern Emerg Med. 2019 Mar 13. [QxMD MEDLINE Link].

31. Rossello X, Wiegerinck RF, Alguersuari J, et al. New electrocardiographic criteria to differentiate acute pericarditis and myocardial infarction. Am J Med. 2014 Mar. 127 (3):233-9. [QxMD MEDLINE Link].

32. [Guideline] Maisch B, Seferovic PM, Ristic AD, et al, for the Task Force on the Diagnosis and Management of Pericardial Diseases of the European Society of Cardiology. Guidelines on the diagnosis and management of pericardial diseases executive summary; The Task force on the diagnosis and management of pericardial diseases of the European society of cardiology. Eur Heart J. 2004 Apr. 25 (7):587-610. [QxMD MEDLINE Link]. [Full Text].

33. Imazio M, Brucato A, Maestroni S, et al. Prevalence of C-reactive protein elevation and time course of normalization in acute pericarditis: implications for the diagnosis, therapy, and prognosis of pericarditis. Circulation. 2011 Mar 15. 123 (10):1092-7. [QxMD MEDLINE Link].

34. Imazio M, Demichelis B, Cecchi E, et al. Cardiac troponin I in acute pericarditis. J Am Coll Cardiol. 2003 Dec 17. 42 (12):2144-8. [QxMD MEDLINE Link].

35. Machado S, Roubille F, Gahide G, et al. Can troponin elevation predict worse prognosis in patients with acute pericarditis?. Ann Cardiol Angeiol (Paris). 2010 Feb. 59 (1):1-7. [QxMD MEDLINE Link].

36. Kim SH, Song JM, Jung IH, Kim MJ, Kang DH, Song JK. Initial echocardiographic characteristics of pericardial effusion determine the pericardial complications. Int J Cardiol. 2009 Aug 14. 136 (2):151-5. [QxMD MEDLINE Link].

37. Hammer MM, Raptis CA, Javidan-Nejad C, Bhalla S. Accuracy of computed tomography findings in acute pericarditis. Acta Radiol. 2014 Dec. 55 (10):1197-202. [QxMD MEDLINE Link].

38. Lazaros G, Antonopoulos AS, Oikonomou EK, et al. Prognostic implications of epicardial fat volume quantification in acute pericarditis. Eur J Clin Invest. 2017 Feb. 47 (2):129-36. [QxMD MEDLINE Link].

39. Gerardin C, Mageau A, Benali K, et atl. Increased FDG-PET/CT pericardial uptake identifies acute pericarditis patients at high risk for relapse. Int J Cardiol. 2018 Nov 15. 271:192-4. [QxMD MEDLINE Link].

40. Yared K, Baggish AL, Picard MH, Hoffmann U, Hung J. Multimodality imaging of pericardial diseases. JACC Cardiovasc Imaging. 2010 Jun. 3 (6):650-60. [QxMD MEDLINE Link].

41. Hooper AJ, Celenza A. A descriptive analysis of patients with an emergency department diagnosis of acute pericarditis. Emerg Med J. 2013 Dec. 30 (12):1003-8. [QxMD MEDLINE Link].

42. Imazio M, Demichelis B, Parrini I, et al. Day-hospital treatment of acute pericarditis: a management program for outpatient therapy. J Am Coll Cardiol. 2004 Mar 17. 43 (6):1042-6. [QxMD MEDLINE Link].

43. Imazio M, Brucato A, Mayosi BM, et al. Medical therapy of pericardial diseases: part I: idiopathic and infectious pericarditis. J Cardiovasc Med (Hagerstown). 2010 Oct. 11 (10):712-22. [QxMD MEDLINE Link].

44. Inanc M, Akpek M, Inanc MT, Kaya MG. Acute pericarditis during 5-fluorouracil, docetaxel and cisplatin therapy. Turk Kardiyol Dern Ars. 2012 Sep. 40 (6):532-5. [QxMD MEDLINE Link].

45. Iyoda M, Ajiro Y, Sato K, et al. A case of refractory uremic pleuropericarditis--successful corticosteroid treatment. Clin Nephrol. 2006 Apr. 65 (4):290-3. [QxMD MEDLINE Link].

46. Imazio M, Trinchero R, Brucato A, et al, for the COPPS Investigators. COlchicine for the Prevention of the Post-pericardiotomy Syndrome (COPPS): a multicentre, randomized, double-blind, placebo-controlled trial. Eur Heart J. 2010 Nov. 31 (22):2749-54. [QxMD MEDLINE Link].

47. Imazio M, Brucato A, Cemin R, et al, for the ICAP Investigators. A randomized trial of colchicine for acute pericarditis. N Engl J Med. 2013 Oct 17. 369 (16):1522-8. [QxMD MEDLINE Link].

48. Nakayama Y, Ohtani Y, Kobayakawa N, Kobayashi J, Kaneko Y, Aoyagi T. A case of early phase dialysis associated effusive constrictive pericarditis with distinct surgical findings. Int Heart J. 2009 Sep. 50 (5):685-91. [QxMD MEDLINE Link].

49. Thompson JL, Burkhart HM, Dearani JA, Cetta F, Oh JK, Schaff HV. Pericardiectomy for pericarditis in the pediatric population. Ann Thorac Surg. 2009 Nov. 88 (5):1546-50. [QxMD MEDLINE Link].

50. Bennett JA, Haramati LB. CT of bronchopericardial fistula: an unusual complication of multidrug-resistant tuberculosis in HIV infection. AJR Am J Roentgenol. 2000 Sep. 175 (3):819-20. [QxMD MEDLINE Link].

51. Adler Y, Finkelstein Y, Guindo J, et al. Colchicine treatment for recurrent pericarditis. A decade of experience. Circulation. 1998 Jun 2. 97 (21):2183-5. [QxMD MEDLINE Link].

52. Adler Y, Guindo J, Finkelstein Y, et al. Colchicine for large pericardial effusion. Clin Cardiol. 1998 Feb. 21 (2):143-4. [QxMD MEDLINE Link].

53. Kuo If, Pearson GJ, Koshman SL. Colchicine for the primary and secondary prevention of pericarditis: an update. Ann Pharmacother. 2009 Dec. 43 (12):2075-81. [QxMD MEDLINE Link].

54. Imazio M, Brucato A, Cemin R, et al, for the CORP (COlchicine for Recurrent Pericarditis) Investigators. Colchicine for recurrent pericarditis (CORP): a randomized trial. Ann Intern Med. 2011 Oct 4. 155 (7):409-14. [QxMD MEDLINE Link].

55. Markel G, Imazio M, Brucato A, Adler Y. Prevention of recurrent pericarditis with colchicine in 2012. Clin Cardiol. 2013 Mar. 36 (3):125-8. [QxMD MEDLINE Link].

56. Alabed S, Cabello JB, Irving GJ, Qintar M, Burls A. Colchicine for pericarditis. Cochrane Database Syst Rev. 2014 Aug 28. 8:CD010652. [QxMD MEDLINE Link].

57. McNamara N, Ibrahim A, Satti Z, Ibrahim M, Kiernan TJ. Acute pericarditis: a review of current diagnostic and management guidelines. Future Cardiol. 2019 Mar. 15 (2):119-26. [QxMD MEDLINE Link].

Sean Spangler, MD Cardiologist, William Beaumont Army Medical Center

Sean Spangler, MD is a member of the following medical societies: American College of Cardiology, American College of Physicians

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Philip J Gentlesk, MD Director, Cardiac Electrophysiology, Section of Cardiovascular Disease, Brooke Army Medical Center

Philip J Gentlesk, MD is a member of the following medical societies: American College of Cardiology, Christian Medical and Dental Associations

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Terrence X O'Brien, MD, MS, FACC Professor of Medicine/Cardiology, Director, Clinical Cardiovascular Research, Medical University of South Carolina College of Medicine; Director, Echocardiography Laboratory, Veterans Affairs Medical Center of Charleston

Terrence X O'Brien, MD, MS, FACC is a member of the following medical societies: American College of Cardiology, American Heart Association, American Society of Echocardiography, Heart Failure Society of America, South Carolina Medical Association

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George R Aronoff, MD Director, Professor, Departments of Internal Medicine and Pharmacology, Section of Nephrology, Kidney Disease Program, University of Louisville School of Medicine

George R Aronoff, MD is a member of the following medical societies: American Federation for Medical Research, American Society of Nephrology, Kentucky Medical Association, and National Kidney Foundation

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Vecihi Batuman, MD, FACP, FASN Professor of Medicine, Section of Nephrology-Hypertension, Tulane University School of Medicine; Chief, Medicine Service, Southeast Louisiana Veterans Health Care System

Vecihi Batuman, MD, FACP, FASN is a member of the following medical societies: American College of Physicians, American Society of Hypertension, American Society of Nephrology, and International Society of Nephrology

Disclosure: Nothing to disclose.

David FM Brown, MD Associate Professor, Division of Emergency Medicine, Harvard Medical School; Vice Chair, Department of Emergency Medicine, Massachusetts General Hospital

David FM Brown, MD is a member of the following medical societies: American College of Emergency Physicians and Society for Academic Emergency Medicine

Disclosure: Nothing to disclose.

Steven J Compton, MD, FACC, FACP Director of Cardiac Electrophysiology, Alaska Heart Institute, Providence and Alaska Regional Hospitals

Steven J Compton, MD, FACC, FACP is a member of the following medical societies: Alaska State Medical Association, American College of Cardiology, American College of Physicians, American Heart Association, American Medical Association, and Heart Rhythm Society

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Christopher A Fly, MD Assistant Professor, Department of Emergency Medicine, Medical College of Georgia

Christopher A Fly, MD is a member of the following medical societies: American College of Emergency Physicians

Disclosure: Nothing to disclose.

Anupama Gowda, MBBS, MD Consulting Staff, Atlanta Nephrology Associates, PC

Disclosure: Nothing to disclose.

Eric L Legome, MD Chief, Department of Emergency Medicine, Kings County Hospital Center; Associate Professor, Department of Emergency Medicine, New York Medical College

Eric L Legome, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Emergency Medicine, American College of Emergency Physicians, Council of Emergency Medicine Residency Directors, and Society for Academic Emergency Medicine

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James W Lohr, MD Professor, Department of Internal Medicine, Division of Nephrology, Fellowship Program Director, University of Buffalo State University of New York School of Medicine and Biomedical Sciences

James W Lohr, MD is a member of the following medical societies: American College of Physicians, American Heart Association, American Society of Nephrology, and Central Society for Clinical Research

Disclosure: Genzyme Honoraria Speaking and teaching

G Shawn Lynchard, MD Consulting Cardiologist, Medical Director of Cardiac Care Unit, Congestive Heart Failure Clinic, and ECG and Stress Testing Clinic, Brooke Army Medical Center

G Shawn Lynchard, MD is a member of the following medical societies: American College of Cardiology and American College of Physicians

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Chike Magnus Nzerue, MD Associate Dean for Clinical Affairs, Vice-Chairman of Internal Medicine, Meharry Medical College

Chike Magnus Nzerue, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Physicians, American College of Physicians-American Society of Internal Medicine, American Society of Nephrology, and National Kidney Foundation

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David A Peak, MD Assistant Residency Director of Harvard Affiliated Emergency Medicine Residency, Attending Physician, Massachusetts General Hospital; Consulting Staff, Department of Hyperbaric Medicine, Massachusetts Eye and Ear Infirmary

David A Peak, MD is a member of the following medical societies: American College of Emergency Physicians, American Medical Association, Society for Academic Emergency Medicine, and Undersea and Hyperbaric Medical Society

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Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Medscape Salary Employment

Verena T Valley, MD Associate Professor, Director of Ultrasound, Department of Emergency Medicine, University of Mississippi School of Medicine; Consulting Staff, Department of Emergency Medicine, Singing River Hospital System, Singing River Hospital, and Ocean Springs Hospital

Verena T Valley, MD is a member of the following medical societies: American College of Emergency Physicians

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