Medication Summary
The goals of pharmacotherapy are to reduce morbidity and to prevent complications.
Generally, outpatient medications consist of the anticoagulant warfarin and any antiarrhythmic used to treat atrial fibrillation or flutter, if present. Diuretics may be needed depending on the volume status of the patient.
Antiarrhythmic agents
Class Summary
Alter the electrophysiologic mechanisms responsible for arrhythmia.
Digoxin (Lanoxin)
Cardiac glycoside with direct inotropic effects and indirect effects on the cardiovascular system. Acts directly on cardiac muscle and increases myocardial systolic contractions. Indirect actions result in increased carotid sinus nerve activity and enhanced sympathetic withdrawal for any given increase in mean arterial pressure.
Anticoagulants
Class Summary
Used for prophylaxis and treatment of venous thrombosis, pulmonary embolism, and thromboembolic disorders.
Warfarin (Coumadin)
Interferes with hepatic synthesis of vitamin K–dependent coagulation factors. Tailor dose to maintain an INR in the range of 2-3.
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Tricuspid Stenosis. A representation of a stenotic tricuspid valve. This image demonstrates fusion of the commissures (shown as dotted lines).