Protein Contact Dermatitis Questions & Answers

1. Hjorth N, Roed-Petersen J. Occupational protein contact dermatitis in food handlers. Contact Dermatitis. 1976 Feb. 2 (1):28-42. [QxMD MEDLINE Link].

2. Helaskoski E, Suojalehto H, Kuuliala O, Aalto-Korte K. Occupational contact urticaria and protein contact dermatitis: causes and concomitant airway diseases. Contact Dermatitis. 2017 Dec. 77 (6):390-396. [QxMD MEDLINE Link].

3. Veien NK, Hattel T, Justesen O, Nørholm A. Causes of eczema in the food industry. Derm Beruf Umwelt. 1983. 31(3):84-6. [QxMD MEDLINE Link].

4. Barbaud A. Mechanism and diagnosis of protein contact dermatitis. Curr Opin Allergy Clin Immunol. 2020 Apr. 20 (2):117-121. [QxMD MEDLINE Link].

5. Barbaud A, Poreaux C, Penven E, Waton J. Occupational protein contact dermatitis. Eur J Dermatol. 2015 Nov-Dec. 25 (6):527-34. [QxMD MEDLINE Link].

6. Jones HE, Reinhardt JH, Rinaldi MG. Immunologic susceptibility to chronic dermatophytosis. Arch Dermatol. 1974 Aug. 110(2):213-20. [QxMD MEDLINE Link].

7. Rundle CW, Bergman D, Goldenberg A, Jacob SE. Contact dermatitis considerations in atopic dermatitis. Clin Dermatol. 2017 Jul - Aug. 35 (4):367-374. [QxMD MEDLINE Link].

8. Wang LF, Lin JY, Hsieh KH, Lin RH. Epicutaneous exposure of protein antigen induces a predominant Th2-like response with high IgE production in mice. J Immunol. 1996 Jun 1. 156 (11):4077-82. [QxMD MEDLINE Link].

9. Lehto M, Koivuluhta M, Wang G, Amghaiab I, Majuri ML, Savolainen K. Epicutaneous natural rubber latex sensitization induces T helper 2-type dermatitis and strong prohevein-specific IgE response. J Invest Dermatol. 2003 Apr. 120(4):633-40. [QxMD MEDLINE Link].

10. Albanesi M, Pasculli C, Giliberti L, Rossi MP, Di Bona D, Caiaffa MF, et al. Immunological characterization of onion (Allium cepa) allergy. Postepy Dermatol Alergol. 2019 Feb. 36 (1):98-103. [QxMD MEDLINE Link].

11. Janssens V, Morren M, Dooms-Goossens A, Degreef H. Protein contact dermatitis: myth or reality?. Br J Dermatol. 1995 Jan. 132(1):1-6. [QxMD MEDLINE Link].

12. Levin C, Warshaw E. Protein contact dermatitis: allergens, pathogenesis, and management. Dermatitis. 2008 Sep-Oct. 19(5):241-51. [QxMD MEDLINE Link].

13. Obtułowicz A, Pirowska M, Wojas-Pelc A. Contact eczema of hands caused by contact with potato protein. Ann Agric Environ Med. 2016 Jun 2. 23 (2):377-8. [QxMD MEDLINE Link].

14. Lukács J, Schliemann S, Elsner P. Occupational contact urticaria caused by food - a systematic clinical review. Contact Dermatitis. 2016 Oct. 75 (4):195-204. [QxMD MEDLINE Link].

15. Alique-García S, Company-Quiroga J, González E, Córdoba S, Garrido-Ríos A, Borbujo J. Protein contact dermatitis caused by flours in a pastry chef. Contact Dermatitis. 2019 Jun. 80 (6):403-404. [QxMD MEDLINE Link].

16. Kishimoto I, Kambe N, Nguyen CTH, Matsuda T, Nomura Y, Uetsu N, et al. Protein contact dermatitis induced by cabbage with recurrent symptoms after oral intake. J Dermatol. 2017 Oct. 44 (10):e252-e253. [QxMD MEDLINE Link].

17. Hannuksela M. Protein Contact Dermatitis. Frosch PJ, Torkil M, Lepoittevin J-P. Contact Dermatitis. 4th. Berlin: Springer; 2006. 345-348.

18. Hansen KS, Petersen HO. Protein contact dermatitis in slaughterhouse workers. Contact Dermatitis. 1989 Oct. 21(4):221-4. [QxMD MEDLINE Link].

19. Barbaud A, Poreaux C, Penven E, Waton J. Occupational protein contact dermatitis. Eur J Dermatol. 2015 Nov-Dec. 25 (6):527-34. [QxMD MEDLINE Link].

20. Vester L, Thyssen JP, Menné T, Johansen JD. Occupational food-related hand dermatoses seen over a 10-year period. Contact Dermatitis. 2012 May. 66 (5):264-70. [QxMD MEDLINE Link].

21. Loddé B, Cros P, Roguedas-Contios AM, Pougnet R, Lucas D, Dewitte JD, et al. Occupational contact dermatitis from protein in sea products: who is the most affected, the fisherman or the chef?. J Occup Med Toxicol. 2017. 12:4. [QxMD MEDLINE Link].

22. Pongpairoj K, Ale I, Andersen KE, Bruze M, Diepgen TL, Elsner PU, et al. Proposed ICDRG Classification of the Clinical Presentation of Contact Allergy. Dermatitis. 2016 Sep 7. [QxMD MEDLINE Link].

23. Kanerva L. Occupational protein contact dermatitis and paronychia from natural rubber latex. J Eur Acad Dermatol Venereol. 2000 Nov. 14 (6):504-6. [QxMD MEDLINE Link].

24. Hernández-Bel P, de la Cuadra J, García R, Alegre V. [Protein contact dermatitis: review of 27 cases]. Actas Dermosifiliogr. 2011 Jun. 102 (5):336-43. [QxMD MEDLINE Link].

25. Warshaw E, Lee G, Storrs FJ. Hand dermatitis: a review of clinical features, therapeutic options, and long-term outcomes. Am J Contact Dermat. 2003 Sep. 14 (3):119-37. [QxMD MEDLINE Link].

26. Sung CT, McGowan MA, Machler BC, Jacob SE. Systemic Treatments for Allergic Contact Dermatitis. Dermatitis. 2019 Jan/Feb. 30 (1):46-53. [QxMD MEDLINE Link].

27. Mercader P, de la Cuadra-Oyanguren J, Rodriguez-Serna M, Pitarch-Bort G, Fortea-Baixauli JM. Treatment of protein contact dermatitis with topical tacrolimus. Acta Derm Venereol. 2005. 85(6):555-6. [QxMD MEDLINE Link].

Cheryl Levin, MD Resident Physician, Department of Dermatology, University of Minnesota Medical School

Cheryl Levin, MD is a member of the following medical societies: American Academy of Dermatology, Women's Dermatologic Society, Medical Dermatology Society

Disclosure: Nothing to disclose.

David F Butler, MD Former Section Chief of Dermatology, Central Texas Veterans Healthcare System; Professor of Dermatology, Texas A&M University College of Medicine; Founding Chair, Department of Dermatology, Scott and White Clinic

David F Butler, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, Association of Military Dermatologists, Phi Beta Kappa, Texas Dermatological Society

Disclosure: Nothing to disclose.

Jeffrey P Callen, MD Professor of Medicine (Dermatology), Chief, Division of Dermatology, University of Louisville School of Medicine

Jeffrey P Callen, MD is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, American College of Physicians, American College of Rheumatology

Disclosure: Received income in an amount equal to or greater than $250 from: Biogen US (Adjudicator for study entry cutaneous lupus erythematosus); Priovant (Adjudicator for entry into a dermatomyositis study); IQVIA (Serono - adjudicator for a study of cutaneous LE) <br/>Received honoraria from UpToDate for author/editor; Received royalty from Elsevier for book author/editor; Received dividends from trust accounts, but I do not control these accounts, and have directed our managers to divest pharmaceutical stocks as is fiscally prudent from Stock holdings in various trust accounts include some pharmaceutical companies and device makers for these trust accounts for: Stocks held in various trust accounts: Allergen; Amgen; Pfizer; 3M; Johnson and Johnson; Merck; Abbott Laboratories; AbbVie; Procter and Gamble;; Celgene; Gilead; CVS; Walgreens; Bristol-Myers Squibb.

Dirk M Elston, MD Professor and Chairman, Department of Dermatology and Dermatologic Surgery, Medical University of South Carolina College of Medicine

Dirk M Elston, MD is a member of the following medical societies: American Academy of Dermatology

Disclosure: Nothing to disclose.

Robert A Schwartz, MD, MPH Professor and Head of Dermatology, Professor of Pathology, Professor of Pediatrics, Professor of Medicine, Rutgers New Jersey Medical School

Robert A Schwartz, MD, MPH is a member of the following medical societies: Alpha Omega Alpha, American Academy of Dermatology, New York Academy of Medicine, Royal College of Physicians of Edinburgh, Sigma Xi, The Scientific Research Honor Society

Disclosure: Nothing to disclose.

Erin M Warshaw, MD, MS Associate Professor, Clinical Scholar Track and Co-Director of Contact Dermatitis Clinic, Department of Dermatology, University of Minnesota Medical School; Chief of Dermatology, Division of Dermatology, Minneapolis Veterans Affairs Medical Center

Erin M Warshaw, MD, MS is a member of the following medical societies: American Contact Dermatitis Society and Women's Dermatologic Society

Disclosure: Nothing to disclose.

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