Toxic Shock Syndrome Questions & Answers

Updated: Oct 08, 2020
  • Author: Ramesh Venkataraman, MBBS; Chief Editor: Michael R Pinsky, MD, CM, Dr(HC), FCCP, FAPS, MCCM  more...
  • Print
Questions & Answers

Overview

What is toxic shock syndrome (TSS)?

What causes toxic shock syndrome (TSS)?

What is the pathophysiology of toxic shock syndrome (TSS)?

What are the mechanism of shock and tissue destruction in the pathophysiology of toxic shock syndrome (TSS)?

What is the risk factors for the development of toxic shock syndrome (TSS)?

What is the prevalence of toxic shock syndrome (TSS) in the US?

What are the racial predilections of toxic shock syndrome (TSS)?

How does the prevalence of toxic shock syndrome (TSS) vary by sex?

Which age groups have the highest prevalence of toxic shock syndrome (TSS)?

What is the prognosis of toxic shock syndrome (TSS)?

What should be included in patient education about toxic shock syndrome (TSS)?

Presentation

What are the clinical presentations of toxic shock syndrome (TSS)?

Which conditions are associated with toxic shock syndrome (TSS)?

What are the signs and symptoms of toxic shock syndrome (TSS)?

What are the symptoms of influenza-like syndrome in patients with toxic shock syndrome (TSS)?

What types of infections have been reported in patients with in toxic shock syndrome (TSS)?

What are the most common presenting symptoms of toxic shock syndrome (TSS)?

Which patient groups are at higher risk for toxic shock syndrome (TSS)?

Which physical findings are characteristic of toxic shock syndrome (TSS)?

What are cutaneous and mucosal signs and symptoms of toxic shock syndrome (TSS)?

What are the diagnostic criteria toxic shock syndrome (TSS)?

What are the most common presenting symptoms of toxic shock syndrome (TSS)?

Which multiorgan involvement is required for diagnosis of toxic shock syndrome (TSS)?

What are severe complications from toxic shock syndrome (TSS)?

DDX

What are the differential diagnoses for Toxic Shock Syndrome?

Workup

What is the role of complete blood count (CBC) test in the workup of toxic shock syndrome (TSS)?

What is the role of urinalysis in the workup of toxic shock syndrome (TSS)?

What is the role of serum biochemistry in the workup of toxic shock syndrome (TSS)?

What is the role of blood cultures in the workup of toxic shock syndrome (TSS)?

What is the role of gram stain and cultures in the workup of toxic shock syndrome (TSS)?

Which lab abnormalities suggest toxic shock syndrome (TSS)?

How is streptococcal toxic shock syndrome (TSS) diagnosed?

What is the role of imaging studies in the evaluation of toxic shock syndrome (TSS)?

Treatment

What is the role of medications in the management of toxic shock syndrome (TSS)?

What can reduce the risk of mortality from toxic shock syndrome (TSS)?

What are the principles in the management of septic shock, used in the treatment of toxic shock syndrome (TSS)?

Which new antibiotics are used in the treatment of toxic shock syndrome (TSS)?

What is the recommended antibiotic therapy for group A Streptococcus (GAS)-related toxic shock syndrome (TSS)?

What is the recommended antibiotic therapy for staphylococcal toxic shock syndrome (TSS)?

What is the role of IV fluids for the management of toxic shock syndrome (TSS)?

What is the role of IV immunoglobulins in the treatment of toxic shock syndrome (TSS)?

What is the role of hyperbaric oxygen and high-dose corticosteroid therapy in the management of toxic shock syndrome (TSS)?

What is the role of monoclonal antibodies in the management of toxic shock syndrome (TSS)?

What is the role of surgery in the management of toxic shock syndrome (TSS)?

Which specialists should be consulted in the treatment of toxic shock syndrome (TSS)?

How is toxic shock syndrome (TSS) prevented?

Guidelines

Which guidelines are available for the management of toxic shock syndrome (TSS)?

Medications

What is the role of drug treatment for toxic shock syndrome (TSS)?

Which medications in the drug class Antibiotics are used in the treatment of Toxic Shock Syndrome?