Villous Adenoma Differential Diagnoses

1. O'Brien MJ, Winawer SJ, Zauber AG, et al. The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas. Gastroenterology. 1990 Feb. 98(2):371-9. [QxMD MEDLINE Link].

2. Lubner MG, Menias CO, Johnson RJ, Gaballah AH, Shaaban A, Elsayes KM. Villous gastrointestinal tumors: multimodality imaging with histopathologic correlation. Radiographics. 2018 Sep-Oct. 38(5):1370-84. [QxMD MEDLINE Link]. [Full Text].

3. Monkemuller K, Neumann H, Malfertheiner P, Fry LC. Advanced colon polypectomy. Clin Gastroenterol Hepatol. 2009 Jun. 7(6):641-52. [QxMD MEDLINE Link]. [Full Text].

4. Fearon ER. Molecular genetics of colorectal cancer. Annu Rev Pathol. 2011. 6:479-507. [QxMD MEDLINE Link]. [Full Text].

5. Testa U, Pelosi E, Castelli G. Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells. Med Sci (Basel). 2018 Apr 13. 6(2):31. [QxMD MEDLINE Link]. [Full Text].

6. Bommer GT, Fearon ER. Molecular abnormalities in colon and rectal cancer. In: Mendelsohn J, Howley PM, Israel MA, et al, eds. The Molecular Basis of Cancer. 3rd ed. Philadelphia, Pa: Saunders; 2008. 409-22.

7. Pettersson L, Tranberg J, Abrahamsson K, Pettersson S, Sillen U, Jonsson O. Half century of followup after ureterosigmoidostomy performed in early childhood. J Urol. 2013 May. 189(5):1870-5. [QxMD MEDLINE Link].

8. Ismail A, Lance P. Colorectal adenomas. In: Johnson, LR, ed. Encyclopedia of Gastroenterology. Cambridge, Massachusetts: Academic Press; 2003. Vol 1: 466-70.

9. Corley DA, Jensen CD, Marks AR, et al. Variation of adenoma prevalence by age, sex, race, and colon location in a large population: implications for screening and quality programs. Clin Gastroenterol Hepatol. 2013 Feb. 11(2):172-80. [QxMD MEDLINE Link]. [Full Text].

10. Ferlitsch M, Reinhart K, Pramhas S, et al. Sex-specific prevalence of adenomas, advanced adenomas, and colorectal cancer in individuals undergoing screening colonoscopy. JAMA. 2011 Sep 28. 306(12):1352-8. [QxMD MEDLINE Link].

11. Bond JH. Colon polyps and cancer. Endoscopy. 2001 Jan. 33(1):46-54. [QxMD MEDLINE Link].

12. Gibbs ER, Walton GF, Kent RB 3rd, Laws HL. Villous tumors of the ampulla Vater. Am Surg. 1997 Jun. 63(6):467-71. [QxMD MEDLINE Link].

13. Cazacu SM, Saftoiu A, Iordache S, et al. Factors predicting occurrence and therapeutic choice in malignant colorectal polyps: a study of 13 years of colonoscopic polypectomy. Rom J Morphol Embryol. 2021 Oct-Dec. 62(4):917-28. [QxMD MEDLINE Link]. [Full Text].

14. Fairley KJ, Li J, Komar M, Steigerwalt N, Erlich P. Predicting the risk of recurrent adenoma and incident colorectal cancer based on findings of the baseline colonoscopy. Clin Transl Gastroenterol. 2014 Dec 4. 5:e64. [QxMD MEDLINE Link].

15. Wark PA, Wu K, van 't Veer P, Fuchs CF, Giovannucci EL. Family history of colorectal cancer: a determinant of advanced adenoma stage or adenoma multiplicity?. Int J Cancer. 2009 Jul 15. 125(2):413-20. [QxMD MEDLINE Link].

16. Cotton PB, Durkalski VL, Pineau BC, et al. Computed tomographic colonography (virtual colonoscopy): a multicenter comparison with standard colonoscopy for detection of colorectal neoplasia. JAMA. 2004 Apr 14. 291(14):1713-9. [QxMD MEDLINE Link].

17. Pickhardt PJ, Choi JR, Hwang I, et al. Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults. N Engl J Med. 2003 Dec 4. 349(23):2191-200. [QxMD MEDLINE Link]. [Full Text].

18. Kadari M, Subhan M, Saji Parel N, et al. CT colonography and colorectal carcinoma: current trends and emerging developments. Cureus. 2022 May. 14(5):e24916. [QxMD MEDLINE Link]. [Full Text].

19. van der Meulen MP, Lansdorp-Vogelaar I, Goede SL, et al. Colorectal cancer: cost-effectiveness of colonoscopy versus CT colonography screening with participation rates and costs. Radiology. 2018 Jun. 287(3):901-11. [QxMD MEDLINE Link]. [Full Text].

20. Terhaar Sive Droste JS, Craanen ME, et al. Colonoscopic yield of colorectal neoplasia in daily clinical practice. World J Gastroenterol. 2009 Mar 7. 15(9):1085-92. [QxMD MEDLINE Link]. [Full Text].

21. Martinez ME, Baron JA, Lieberman DA, et al. A pooled analysis of advanced colorectal neoplasia diagnoses after colonoscopic polypectomy. Gastroenterology. 2009 Mar. 136(3):832-41. [QxMD MEDLINE Link].

22. de Jonge V, Sint Nicolaas J, van Leerdam ME, Kuipers EJ, Veldhuyzen van Zanten SJ. Systematic literature review and pooled analyses of risk factors for finding adenomas at surveillance colonoscopy. Endoscopy. 2011 Jul. 43(7):560-72. [QxMD MEDLINE Link].

23. Denis B, Peters C, Chapelain C, et al. Diagnostic accuracy of community pathologists in the interpretation of colorectal polyps. Eur J Gastroenterol Hepatol. 2009 Oct. 21(10):1153-60. [QxMD MEDLINE Link].

24. Bokemeyer B, Bock H, Huppe D, et al. Screening colonoscopy for colorectal cancer prevention: results from a German online registry on 269000 cases. Eur J Gastroenterol Hepatol. 2009 Jun. 21(6):650-5. [QxMD MEDLINE Link].

25. Chandrasekhara V, Kumta NA, Abu Dayyeh BK, et al. Endoscopic polypectomy devices. VideoGIE. 2021 Jul. 6(7):283-3. [QxMD MEDLINE Link]. [Full Text].

26. Farnell MB, Sakorafas GH, Sarr MG, et al. Villous tumors of the duodenum: reappraisal of local vs. extended resection. J Gastrointest Surg. 2000 Jan-Feb. 4(1):13-21, discussion 22-3. [QxMD MEDLINE Link].

27. [Guideline] Gupta S, Lieberman D, Anderson JC, et al. Recommendations for follow-up after colonoscopy and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer. Gastrointest Endosc. 2020 Mar. 91(3):463-485.e5. [QxMD MEDLINE Link]. [Full Text].

28. DuBois RN, Giardiello FM, Smalley WE. Nonsteroidal anti-inflammatory drugs, eicosanoids, and colorectal cancer prevention. Gastroenterol Clin North Am. 1996 Dec. 25(4):773-91. [QxMD MEDLINE Link].

29. Cole BF, Logan RF, Halabi S, et al. Aspirin for the chemoprevention of colorectal adenomas: meta-analysis of the randomized trials. J Natl Cancer Inst. 2009 Feb 18. 101(4):256-66. [QxMD MEDLINE Link].

30. Baron JA, Cole BF, Sandler RS, et al. A randomized trial of aspirin to prevent colorectal adenomas. N Engl J Med. 2003 Mar 6. 348(10):891-9. [QxMD MEDLINE Link].

31. Bond JH. Polyp guideline: diagnosis, treatment, and surveillance for patients with colorectal polyps. Practice Parameters Committee of the American College of Gastroenterology. Am J Gastroenterol. 2000 Nov. 95(11):3053-63. [QxMD MEDLINE Link].

32. Bond JH. Polyp guideline: diagnosis, treatment, and surveillance for patients with nonfamilial colorectal polyps. The Practice Parameters Committee of the American College of Gastroenterology. Ann Intern Med. 1993 Oct 15. 119(8):836-43. [QxMD MEDLINE Link].

33. Day DW, Morson BC. The adenoma-carcinoma sequence. Morson BC, ed. The Pathogenesis of Colorectal Cancer. Philadelphia: WB Saunders; 1978. 58-71.

34. Itzkowitz SH, Kim YS. Colonic polyps and polyposis syndromes. Feldman M, Scharschmidt BF, Sleisenger MH, eds. Sleisenger and Fordtran's Gastrointestinal and Liver Disease: Pathophysiology, Diagnosis, and Management. 6th ed. Philadelphia: WB Saunders; 1997. 467-71.

35. Sandler RS, Halabi S, Baron JA, et al. A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer. N Engl J Med. 2003 Mar 6. 348(10):883-90. [QxMD MEDLINE Link].

36. Schrock TR. Colonoscopy for colorectal cancer: too much, too little, just right. ASGE Distinguished Lecture 1993. Gastrointest Endosc. 1993 Nov-Dec. 39(6):848-51. [QxMD MEDLINE Link].

37. Seitz U, Bohnacker S, Seewald S, et al. Is endoscopic polypectomy an adequate therapy for malignant colorectal adenomas? Presentation of 114 patients and review of the literature. Dis Colon Rectum. 2004 Nov. 47(11):1789-96; discussion 1796-7. [QxMD MEDLINE Link].

38. Stryker SJ, Wolff BG, Culp CE, Libbe SD, Ilstrup DM, MacCarty RL. Natural history of untreated colonic polyps. Gastroenterology. 1987 Nov. 93(5):1009-13. [QxMD MEDLINE Link].

39. Winawer SJ, Zauber AG, Fletcher RH, et al. Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer Society. Gastroenterology. 2006 May. 130(6):1872-85. [QxMD MEDLINE Link].

40. Jeong YH, Kim KO, Park CS, Kim SB, Lee SH, Jang BI. Risk factors of advanced adenoma in small and diminutive colorectal polyp. J Korean Med Sci. 2016 Sep. 31(9):1426-30. [QxMD MEDLINE Link].

41. Veettil SK, Wong TY, Loo YS, et al. Role of diet in colorectal cancer incidence: umbrella review of meta-analyses of prospective observational studies. JAMA Netw Open. 2021 Feb 1. 4(2):e2037341. [QxMD MEDLINE Link]. [Full Text].

42. Rex DK, Schoenfeld PS, Cohen J, et al. Quality indicators for colonoscopy. Am J Gastroenterol. 2015 Jan. 110(1):72-90. [QxMD MEDLINE Link]. [Full Text].

Alnoor Ramji, MD, FRCPC Department of Medicine, Division of Gastroenterology, University of British Columbia Faculty of Medicine, Canada

Alnoor Ramji, MD, FRCPC is a member of the following medical societies: Canadian Society of Internal Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Burt Cagir, MD, FACS Associate Regional Dean and Professor of Surgery, Geisinger Commonwealth School of Medicine; Director, General Surgery Residency Program, Executive Director, Donald Guthrie Foundation for Research and Education, Guthrie Robert Packer Hospital; Medical Director, Guthrie/RPH Skills and Simulation Lab; Associate in Surgery, Guthrie Robert Packer Hospital and Corning Hospital

Burt Cagir, MD, FACS is a member of the following medical societies: American College of Surgeons, Association of Program Directors in Surgery, Society for Surgery of the Alimentary Tract

Disclosure: Nothing to disclose.

Manoop S Bhutani, MD Professor, Co-Director, Center for Endoscopic Research, Training and Innovation (CERTAIN), Director, Center for Endoscopic Ultrasound, Department of Medicine, Division of Gastroenterology, University of Texas Medical Branch; Director, Endoscopic Research and Development, The University of Texas MD Anderson Cancer Center

Manoop S Bhutani, MD is a member of the following medical societies: American Association for the Advancement of Science, American College of Gastroenterology, American College of Physicians, American Gastroenterological Association, American Institute of Ultrasound in Medicine, American Society for Gastrointestinal Endoscopy

Disclosure: Nothing to disclose.

Eric M Yoshida, MD, MHSc, FRCPC, FACP Program Director of Adult Gastroenterology Training Program, Assistant Professor, Department of Medicine, Division of Gastroenterology, University of British Columbia Faculty of Medicine, Canada

Disclosure: Nothing to disclose.

• Print this section
• Print the entire contents of
• Print the entire contents of article