Boerhaave Syndrome Medication

Updated: Dec 06, 2018
  • Author: Praveen K Roy, MD, MSc; Chief Editor: Philip O Katz, MD, FACP, FACG  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.



Class Summary

Empiric antimicrobial therapy must be comprehensive and should cover all likely pathogens in the context of the clinical setting. A broad-spectrum antibiotic, such as imipenem/cilastatin (Primaxin), is recommended. Broad spectrum intravenous antibiotics should be continued for 7 to 14 days.

Imipenem/cilastatin (Primaxin)

Offers good broad-spectrum coverage. For treatment of multiple-organism infections in which other agents do not have wide-spectrum coverage or are contraindicated due to potential for toxicity.