Celiac Disease (Sprue) Medication

1. Ludvigsson JF, Zingone F, Tomson T, Ekbom A, Ciacci C. Increased risk of epilepsy in biopsy-verified celiac disease: A population-based cohort study. Neurology. 2012 May 1. 78(18):1401-7. [QxMD MEDLINE Link].

2. [Guideline] Rubio-Tapia A, Hill ID, Kelly CP, Calderwood AH, Murray JA, American College of Gastroenterology. ACG clinical guidelines: diagnosis and management of celiac disease. Am J Gastroenterol. 2013 May. 108(5):656-76; quiz 677. [QxMD MEDLINE Link].

3. Green PH, Cellier C. Celiac disease. N Engl J Med. 2007 Oct 25. 357(17):1731-43. [QxMD MEDLINE Link].

4. Martucciello S, Paolella G, Esposito C, Lepretti M, Caputo I. Anti-type 2 transglutaminase antibodies as modulators of type 2 transglutaminase functions: a possible pathological role in celiac disease. Cell Mol Life Sci. 2018 Nov. 75(22):4107-24. [QxMD MEDLINE Link].

5. Kagnoff MF. Celiac disease: pathogenesis of a model immunogenetic disease. J Clin Invest. 2007 Jan. 117(1):41-9. [QxMD MEDLINE Link].

6. Green PH, Lebwohl B, Greywoode R. Celiac disease. J Allergy Clin Immunol. 2015 May. 135(5):1099-106; quiz 1107. [QxMD MEDLINE Link].

7. Kelly CP, Bai JC, Liu E, Leffler DA. Advances in diagnosis and management of celiac disease. Gastroenterology. 2015 May. 148(6):1175-86. [QxMD MEDLINE Link].

8. Glissen Brown JR, Singh P. Coeliac disease. Paediatr Int Child Health. 2019 Feb. 39(1):23-31. [QxMD MEDLINE Link].

9. Tursi A, Brandimarte G, Giorgetti GM. Prevalence of antitissue transglutaminase antibodies in different degrees of intestinal damage in celiac disease. J Clin Gastroenterol. 2003 Mar. 36(3):219-21. [QxMD MEDLINE Link].

10. Rubio-Tapia A, Kyle RA, Kaplan EL, et al. Increased prevalence and mortality in undiagnosed celiac disease. Gastroenterology. 2009 Jul. 137(1):88-93. [QxMD MEDLINE Link]. [Full Text].

11. Singh P, Arora A, Strand TA, et al. Global prevalence of celiac disease: systematic review and meta-analysis. Clin Gastroenterol Hepatol. 2018 Jun. 16(6):823-36.e2. [QxMD MEDLINE Link].

12. Yachha SK, Misra S, Malik AK, Nagi B, Mehta S. Spectrum of malabsorption syndrome in north Indian children. Indian J Gastroenterol. 1993 Oct. 12(4):120-5. [QxMD MEDLINE Link].

13. Cummins AG, Roberts-Thomson IC. Prevalence of celiac disease in the Asia-Pacific region. J Gastroenterol Hepatol. 2009 Aug. 24(8):1347-51. [QxMD MEDLINE Link].

14. Rashtak S, Murray JA. Celiac disease in the elderly. Gastroenterol Clin North Am. 2009 Sep. 38(3):433-46. [QxMD MEDLINE Link].

15. Mollazadegan K, Kugelberg M, Lindblad BE, Ludvigsson JF. Increased risk of cataract among 28,000 patients with celiac disease. Am J Epidemiol. 2011 Jul 15. 174(2):195-202. [QxMD MEDLINE Link].

16. Rubio-Tapia A, Herman ML, Ludvigsson JF, et al. Severe spruelike enteropathy associated with olmesartan. Mayo Clin Proc. 2012 Aug. 87(8):732-8. [QxMD MEDLINE Link]. [Full Text].

17. Marthey L, Cadiot G, Seksik P, et al. Olmesartan-associated enteropathy: results of a national survey. Aliment Pharmacol Ther. 2014 Nov. 40(9):1103-9. [QxMD MEDLINE Link]. [Full Text].

18. Negro A, Rossi GM, Santi R, Iori V, De Marco L. A case of severe sprue-like enteropathy associated with losartan. J Clin Gastroenterol. 2015 Oct. 49(9):794. [QxMD MEDLINE Link].

19. Herman ML, Rubio-Tapia A, Wu TT, Murray JA. A case of severe sprue-like enteropathy associated with valsartan. ACG Case Rep J. 2015 Jan. 2(2):92-4. [QxMD MEDLINE Link]. [Full Text].

20. [Guideline] Duerksen D, Pinto-Sanchez MI, Anca A, et al. Management of bone health in patients with celiac disease: practical guide for clinicians. Can Fam Physician. 2018 Jun. 64 (6):433-8. [QxMD MEDLINE Link].

21. [Guideline] Rubio-Tapia A, Murray JA. Updated guidelines by the European Society for the Study of Coeliac Disease. United European Gastroenterol J. 2019 Jun. 7(5):581-2. [QxMD MEDLINE Link]. [Full Text].

22. [Guideline] Al-Toma A, Volta U, Auricchio R, et al. European Society for the Study of Coeliac Disease (ESsCD) guideline for coeliac disease and other gluten-related disorders. United European Gastroenterol J. 2019 Jun. 7(5):583-613. [QxMD MEDLINE Link]. [Full Text].

23. [Guideline] Husby S, Koletzko S, Korponay-Szabo I, et al. European Society Paediatric Gastroenterology, Hepatology and Nutrition guidelines for diagnosing coeliac disease 2020. J Pediatr Gastroenterol Nutr. 2019 Oct 17. [QxMD MEDLINE Link].

24. Rosen A, Sandstrom O, Carlsson A, et al. Usefulness of symptoms to screen for celiac disease. Pediatrics. 2014 Feb. 133(2):211-8. [QxMD MEDLINE Link]. [Full Text].

25. Lowry F. Current screening guidelines fail to identify celiac disease. Medscape Medical News from WebMD. Available at http://www.medscape.com/viewarticle/819052. January 13, 2014; Accessed: January 25, 2014.

26. Caio G, De Giorgio R, Ursini F, Fanaro S, Volta U. Prevalence of celiac disease serological markers in a cohort of Italian rheumatological patients. Gastroenterol Hepatol Bed Bench. 2018 Summer. 11(3):244-9. [QxMD MEDLINE Link].

27. Kaur N, Bhadada SK, Minz RW, Dayal D, Kochhar R. Interplay between type 1 diabetes mellitus and celiac disease: implications in treatment. Dig Dis. 2018. 36(6):399-408. [QxMD MEDLINE Link]. [Full Text].

28. Mahadev S, Laszkowska M, Sundstrom J, et al. Prevalence of celiac disease in patients with iron deficiency anemia-a systematic review With meta-analysis. Gastroenterology. 2018 Aug. 155(2):374-82.e1. [QxMD MEDLINE Link].

29. Boggs W. Genetic testing might improve diagnosis of celiac disease. Medscape Medical News. September 10, 2013. [Full Text].

30. Anderson RP, Henry MJ, Taylor R, et al. A novel serogenetic approach determines the community prevalence of celiac disease and informs improved diagnostic pathways. BMC Med. 2013 Aug 28. 11(1):188. [QxMD MEDLINE Link]. [Full Text].

31. Errichiello S, Esposito O, Di Mase R, et al. Celiac disease: predictors of compliance with a gluten-free diet in adolescents and young adults. J Pediatr Gastroenterol Nutr. 2010 Jan. 50(1):54-60. [QxMD MEDLINE Link].

32. Benelli E, Zin A, Martelossi S. Celiac disease in children. Minerva Pediatr. 2019 Feb. 71(1):39-46. [QxMD MEDLINE Link].

33. Abutaleb Y. FDA issues new rules for labeling 'gluten-free' foods. Reuters Health Information. August 02, 2013. [Full Text].

34. US Food and Drug Administration. FDA defines "gluten-free" for food labeling [press release]. August 2, 2013. Available at http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm363474.htm. Accessed: August 12, 2013.

35. MacReady N. Celiac disease: new data may change recommendations for kids. Medscape Medical News. Available at http://www.medscape.com/viewarticle/832743. October 2, 2014; Accessed: October 3, 2014.

36. Vriezinga SL, Auricchio R, Bravi E, et al. Randomized feeding intervention in infants at high risk for celiac disease. N Engl J Med. 2014 Oct 2. 371(14):1304-15. [QxMD MEDLINE Link].

37. Lionetti E, Castellaneta S, Francavilla R, et al. Introduction of gluten, HLA status, and the risk of celiac disease in children. N Engl J Med. 2014 Oct 2. 371(14):1295-303. [QxMD MEDLINE Link].

38. Askling J, Linet M, Gridley G, et al. Cancer incidence in a population-based cohort of individuals hospitalized with celiac disease or dermatitis herpetiformis. Gastroenterology. 2002 Nov. 123(5):1428-35. [QxMD MEDLINE Link].

39. Catassi C, Ratsch IM, Fabiani E, et al. Coeliac disease in the year 2000: exploring the iceberg. Lancet. 1994 Jan 22. 343(8891):200-3. [QxMD MEDLINE Link].

40. Collin P, Kaukinen K, Vogelsang H, et al. Antiendomysial and antihuman recombinant tissue transglutaminase antibodies in the diagnosis of coeliac disease: a biopsy-proven European multicentre study. Eur J Gastroenterol Hepatol. 2005 Jan. 17(1):85-91. [QxMD MEDLINE Link].

41. Cristofori F, Fontana C, Magista A, et al. Increased prevalence of celiac disease among pediatric patients with irritable bowel syndrome: a 6-year prospective cohort study. JAMA Pediatr. 2014 Jun. 168(6):555-60. [QxMD MEDLINE Link].

42. Dieterich W, Ehnis T, Bauer M, et al. Identification of tissue transglutaminase as the autoantigen of celiac disease. Nat Med. 1997 Jul. 3(7):797-801. [QxMD MEDLINE Link].

43. Farrell RJ, Kelly CP. Celiac sprue. N Engl J Med. 2002 Jan 17. 346(3):180-8. [QxMD MEDLINE Link].

44. Fasano A, Berti I, Gerarduzzi T, et al. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med. 2003 Feb 10. 163(3):286-92. [QxMD MEDLINE Link].

45. Ferguson A, Arranz E, O'Mahony S. Clinical and pathological spectrum of coeliac disease--active, silent, latent, potential. Gut. 1993 Feb. 34(2):150-1. [QxMD MEDLINE Link].

46. Frellick M. Celiac disease screening should focus on kids with IBS. Medscape [serial online]. Available at http://www.medscape.com/viewarticle/823915. April 21, 2014; Accessed: April 27, 2014.

47. Godkin A, Jewell D. The pathogenesis of celiac disease. Gastroenterology. 1998 Jul. 115(1):206-10. [QxMD MEDLINE Link].

48. Greco L, Romino R, Coto I, et al. The first large population based twin study of coeliac disease. Gut. 2002 May. 50(5):624-8. [QxMD MEDLINE Link].

49. Green PH, Jabri B. Coeliac disease. Lancet. 2003 Aug 2. 362(9381):383-91. [QxMD MEDLINE Link].

50. Harding A. Endoscopy without biopsy may miss many with celiac disease. Reuters Health Information. March 17, 2014. [Full Text].

51. James MW, Scott BB. Coeliac disease: the cause of the various associated disorders?. Eur J Gastroenterol Hepatol. 2001 Sep. 13(9):1119-21. [QxMD MEDLINE Link].

52. Johnson TC, Diamond B, Memeo L, et al. Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol. 2004 Oct. 2(10):888-94. [QxMD MEDLINE Link].

53. Lewis R. Pediatric celiac disease more common with HLA haplotype. Medscape Medical News. Available at http://www.medscape.com/viewarticle/827791. July 3, 2014; Accessed: July 6, 2014.

54. Liu E, Lee HS, Aronsson CA, et al. Risk of pediatric celiac disease according to HLA haplotype and country. N Engl J Med. 2014 Jul 3. 371(1):42-9. [QxMD MEDLINE Link].

55. Mention JJ, Ben Ahmed M, Begue B, et al. Interleukin 15: a key to disrupted intraepithelial lymphocyte homeostasis and lymphomagenesis in celiac disease. Gastroenterology. 2003 Sep. 125(3):730-45. [QxMD MEDLINE Link].

56. Murray JA, Van Dyke C, Plevak MF, et al. Trends in the identification and clinical features of celiac disease in a North American community, 1950-2001. Clin Gastroenterol Hepatol. 2003 Jan. 1(1):19-27. [QxMD MEDLINE Link].

57. Pietzak MM, Schofield TC, McGinniss MJ, Nakamura RM. Stratifying risk for celiac disease in a large at-risk United States population by using HLA alleles. Clin Gastroenterol Hepatol. 2009 Sep. 7(9):966-71. [QxMD MEDLINE Link].

58. Rashtak S, Murray JA. Celiac disease in the elderly. Gastroenterol Clin North Am. 2009 Sep. 38(3):433-46. [QxMD MEDLINE Link].

59. Robson K, Alizart M, Martin J, Nagel R. Coeliac patients are undiagnosed at routine upper endoscopy. PLoS One. 2014. 9(3):e90552. [QxMD MEDLINE Link]. [Full Text].

60. Rostami K, Malekzadeh R, Shahbazkhani B, et al. Coeliac disease in Middle Eastern countries: a challenge for the evolutionary history of this complex disorder?. Dig Liver Dis. 2004 Oct. 36(10):694-7. [QxMD MEDLINE Link].

61. Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology. 2006 Dec. 131(6):1981-2002. [QxMD MEDLINE Link].

62. Salmi TT, Collin P, Korponay-Szabo IR, et al. Endomysial antibody-negative coeliac disease: clinical characteristics and intestinal autoantibody deposits. Gut. 2006 Dec. 55(12):1746-53. [QxMD MEDLINE Link].

63. Sanders DS, Hurlstone DP, McAlindon ME, et al. Antibody negative coeliac disease presenting in elderly people--an easily missed diagnosis. BMJ. 2005 Apr 2. 330(7494):775-6. [QxMD MEDLINE Link].

64. Sategna-Guidetti C, Pulitano R, Grosso S, et al. Serum IgA antiendomysium antibody titers as a marker of intestinal involvement and diet compliance in adult celiac sprue. J Clin Gastroenterol. 1993 Sep. 17(2):123-7. [QxMD MEDLINE Link].

65. Smedby KE, Akerman M, Hildebrand H, et al. Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma. Gut. 2005 Jan. 54(1):54-9. [QxMD MEDLINE Link].

66. Squires JE, Fei L, Cohen MB. Role of celiac disease screening for children with functional gastrointestinal disorders. JAMA Pediatr. 2014 Jun. 168(6):514-5. [QxMD MEDLINE Link].

67. [Guideline] Enns RA, Hookey L, Armstrong D, et al. Clinical practice guidelines for the use of video capsule endoscopy. Gastroenterology. 2017 Feb. 152(3):497-514. [QxMD MEDLINE Link].

68. Bustamante MA, Fernandez-Gil MP, Churruca I, et al. Evolution of gluten content in cereal-based gluten-free products: an overview from 1998 to 2016. Nutrients. 2017 Jan 3. 9(1):[QxMD MEDLINE Link].

Stephan U Goebel, MD Assistant Professor of Gastroenterology and Hepatology, Department of Medicine, Emory University School of Medicine

Stephan U Goebel, MD is a member of the following medical societies: American Gastroenterological Association, American Society for Gastrointestinal Endoscopy

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

BS Anand, MD Professor, Department of Internal Medicine, Division of Gastroenterology, Baylor College of Medicine

BS Anand, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American College of Gastroenterology, American Gastroenterological Association, American Society for Gastrointestinal Endoscopy

Disclosure: Nothing to disclose.

James L Achord, MD Professor Emeritus, Department of Medicine, Division of Digestive Diseases, University of Mississippi School of Medicine

James L Achord, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American College of Gastroenterology, American College of Physicians, American Gastroenterological Association, American Medical Association, American Society for Gastrointestinal Endoscopy, Mississippi State Medical Association, New York Academy of Sciences, Sigma Xi, and Southern Medical Association

Disclosure: Nothing to disclose.

Mounzer Al Samman, MD Assistant Professor, Department of Internal Medicine, Division of Gastroenterology, Texas Tech University School of Medicine

Mounzer Al Al Samman, MD is a member of the following medical societies: American College of Gastroenterology, American College of Physicians, and American Gastroenterological Association

Disclosure: Nothing to disclose.

Jan-Michael A Klapproth, MD Assistant Professor, Department of Medicine, Division of Digestive Diseases, Emory University School of Medicine

Jan-Michael A Klapproth, MD is a member of the following medical societies: American College of Gastroenterology, American Federation for Medical Research, American Gastroenterological Association, and Crohns and Colitis Foundation of America

Disclosure: Nothing to disclose.

Vincent W Yang, MD, PhD R Bruce Logue Professor, Director, Division of Digestive Diseases, Department of Medicine, Professor of Hematology and Oncology, Winship Cancer Institute, Emory University School of Medicine

Vincent W Yang, MD, PhD is a member of the following medical societies: Alpha Omega Alpha, American Gastroenterological Association, American Society for Clinical Investigation, and Association of American Physicians

Disclosure: Nothing to disclose.

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