Cytomegalovirus Colitis Clinical Presentation

Updated: Jan 08, 2017
  • Author: Douglas M Heuman, MD, FACP, FACG, AGAF; Chief Editor: BS Anand, MD  more...
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Patients with cytomegalovirus (CMV) colitis may present with the following symptoms:

  • Fever
  • Anorexia
  • Malaise
  • Weight loss
  • Dehydration
  • Abdominal pain
  • Abdominal distention
  • Nausea
  • Vomiting
  • Chronic watery diarrhea
  • Bloody diarrhea
  • Constipation
  • Worsening symptoms of inflammatory bowel disease [6, 7, 8]

Physical Examination

Patients with cytomegalovirus (CMV)  colitis may exhibit a wide range of abdominal findings depending on the stage of their disease, including the following:

  • Abdominal signs are not present early in the disease.
  • Tenderness may develop in the descending and sigmoid colon as the bowel becomes more involved.
  • Peritoneal signs and fever may be present. If the bowel becomes ischemic or perforates, clinical signs of an acute abdomen may develop.