Cytomegalovirus Colitis Clinical Presentation

Updated: May 17, 2021
  • Author: Douglas M Heuman, MD, FACP, FACG, AGAF; Chief Editor: BS Anand, MD  more...
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Patients with cytomegalovirus (CMV) colitis may present with the following symptoms:

  • Fever

  • Anorexia

  • Malaise

  • Weight loss

  • Dehydration

  • Abdominal pain

  • Abdominal distention

  • Nausea

  • Vomiting

  • Chronic watery diarrhea

  • Bloody diarrhea

  • Constipation

  • Worsening symptoms of inflammatory bowel disease [6, 7, 8, 9]


Physical Examination

Patients with cytomegalovirus (CMV) colitis may exhibit a wide range of abdominal findings depending on the stage of their disease, including the following:

  • Abdominal signs are not present early in the disease.

  • Tenderness may develop in the descending and sigmoid colon as the bowel becomes more involved.

  • Peritoneal signs and fever may be present. If the bowel becomes ischemic or perforates, clinical signs of an acute abdomen may develop.