Esophageal Leiomyoma Differential Diagnoses

Updated: Jan 25, 2023
  • Author: Kavitha Kumbum, MD; Chief Editor: Praveen K Roy, MD, MSc  more...
  • Print

Diagnostic Considerations

Calcification may occur within a leiomyoma; this must be considered in the differential diagnosis of a calcified mediastinal mass.

Leiomyomatosis is a variation of leiomyoma in which multiple leiomyomas develop throughout the length of the esophagus and can be associated with Alport's syndrome. [5] An association also exists between esophageal leiomyomas and MEN type 1, [6] and case reports exist of leiomyomatosis presenting as pseudoachalasia. [7]

Differential Diagnoses