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Sections Hepatitis E
- Overview
- Presentation
- DDx
- Workup
- Treatment
- Guidelines
- Medication
- References
Diagnostic Considerations
Autoimmune hepatitis
Acute hepatitis E presents with histologic and biochemical features of autoimmune hepatitis and, thus, acute HEV infection may be misclassified as de novo onset of autoimmune hepatitis—treatment with immunosuppressants in acutely HEV-infected patients may accelerate histologic progression. [33] Therefore, in patients with autoimmune hepatitis who will be treated with low doses of steroids with or without azathioprine, routine serologic testing of HEV infection is strongly recommended in the initial work-up. Patients with autoimmune hepatitis who develop unexplained elevated liver enzyme levels should also be tested for HEV RNA. [33]
Differential Diagnoses
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Liver injury due to drugs (drug-induced liver injury, particularly isoniazid)
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Tables
Prospere Remy, MD Assistant Professor of Medicine, Albert Einstein College of Medicine; Attending Physician, Department of Internal Medicine, Bronx-Lebanon Hospital Center
Prospere Remy, MD is a member of the following medical societies: American College of Physicians, American Society for Gastrointestinal Endoscopy
Disclosure: Nothing to disclose.
David Widjaja, MD Gastroenterological Consultant, Medistra Hospital, Jakarta, Indonesia
David Widjaja, MD is a member of the following medical societies: American Society for Gastrointestinal Endoscopy, Indonesian Medical Association
Disclosure: Nothing to disclose.
BS Anand, MD Professor, Department of Internal Medicine, Division of Gastroenterology, Baylor College of Medicine
BS Anand, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American College of Gastroenterology, American Gastroenterological Association, American Society for Gastrointestinal Endoscopy
Disclosure: Nothing to disclose.
David Eric Bernstein, MD Director of Hepatology, North Shore University Hospital; Professor of Clinical Medicine, Albert Einstein College of Medicine
David Eric Bernstein, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American College of Gastroenterology, American College of Physicians, American Gastroenterological Association, and American Society for Gastrointestinal Endoscopy
Disclosure: Nothing to disclose.
Kenneth D Flora, MD Adjunct Associate Professor of Medicine, Division of Gastroenterology and Hepatology, Oregon Health Sciences University School of Medicine; Consulting Staff, Department of Gastroenterology, The Oregon Clinic
Kenneth D Flora, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American College of Gastroenterology, and American Gastroenterological Association
Disclosure: Nothing to disclose.
Kenneth Ingram, PAC Assistant Professor, Department of Medicine, Division of Gastroenterology and Hepatology, Oregon Health and Science University School of Medicine
Disclosure: Nothing to disclose.
Sandeep Mukherjee, MB, BCh, MPH, FRCPC Associate Professor, Department of Internal Medicine, Section of Gastroenterology and Hepatology, University of Nebraska Medical Center; Consulting Staff, Section of Gastroenterology and Hepatology, Veteran Affairs Medical Center
Sandeep Mukherjee, MB, BCh, MPH, FRCPC is a member of the following medical societies: Royal College of Physicians and Surgeons of Canada
Disclosure: Merck Honoraria Speaking and teaching; Ikaria Pharmaceuticals Honoraria Board membership
Jonathan M Schwartz, MD Associate Professor, Department of Medicine, Division of Gastroenterology and Hepatology, Oregon Health and Sciences University School of Medicine
Jonathan M Schwartz, MD is a member of the following medical societies: American Association for the Study of Liver Diseases, American Gastroenterological Association, and American Hepato-Pancreato-Biliary Association
Disclosure: Nothing to disclose.
Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference
Disclosure: Medscape Salary Employment
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Sections Hepatitis E
- Overview
- Presentation
- DDx
- Workup
- Treatment
- Guidelines
- Medication
- References
