Intestinal Polypoid Adenomas Differential Diagnoses

Updated: Feb 05, 2018
  • Author: Swati G Patel, MD, MS; Chief Editor: BS Anand, MD  more...
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DDx

Diagnostic Considerations

The differential diagnosis of adenomas includes other polypoid lesions of the gastrointestinal tract. Usually, neoplastic and nonneoplastic mucosal lesions can be endoscopically differentiated from the submucosal polypoid lesions.

Neoplastic lesions to consider include the following:

  • Adenoma

  • Carcinoma

  • Sessile serrated adenoma or polyp

  • Traditional serrated adenoma

Nonneoplastic lesions to consider include the following:

  • Normal mucosa

  • Lymphoid aggregate

  • Hyperplastic polyp

  • Inflammatory polyp

  • Juvenile polyp

  • Hamartomatous polyp

Submucosal lesions to consider include the following:

  • Stromal tumor

  • Neuroendocrine tumor

  • Lipoma

  • Lymphoma

Other conditions to consider include the following:

  • Pneumatosis cystoides intestinalis

  • Colitis cystica profunda

Differential Diagnoses