Pediatric Lipid Disorders in Clinical Practice Questions & Answers

Updated: Jun 27, 2019
  • Author: Henry J Rohrs, III, MD; Chief Editor: Stuart Berger, MD  more...
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Questions & Answers

Overview

What is the physiology of lipids and lipoproteins?

What is the Frederickson Classification of dyslipidemias?

What is the pathophysiology of type I hyperlipoproteinemia (HLP)?

What is the pathophysiology of type II hyperlipoproteinemia (HLP)?

What is the pathophysiology of type III hyperlipoproteinemia (HLP)?

What is the pathophysiology of type IV hyperlipoproteinemia (HLP)?

What is the pathophysiology of type V hyperlipoproteinemia (HLP)?

Which conditions are included in the differential diagnoses of a depressed HDL-C level?

DDX

When is an average of two fasting lipid profiles indicated?

What are the pediatric risk factors for cardiovascular disease?

Workup

What are the AACE/ACE guidelines for interpreting pediatric lipid profiles?

What are the ES/ESE/PES guidelines on assessment, treatment and prevention of pediatric obesity?

How is lipid testing performed in children?

What is the role of pediatric lipid testing in the screening for adult cardiovascular risk?

What are the ACC/AHA guidelines on pediatric lipid testing?

What are the AACE guidelines on pediatric lipid testing?

What are the AACE treatment guidelines for dyslipidemia and prevention of CVD?

What is the National Cholesterol Education Program (NCEP)?

What are the NHLBI guidelines on pediatric lipid screening?

Treatment

What are the ACC/AHA guidelines on the primary prevention of atherosclerotic cardiovascular disease (ASCVD) for children and adolescents?

What are the ACC/AHA guidelines AACE/ACE treatment guidelines for dyslipidemia and prevention of CVD for children and adolescents?

What is the initial treatment for pediatric lipid disorders?

What are the CHILD-1 (Cardiovascular Health Integrated Lifestyle Diet–1) recommendations?

What are the CHILD-2 (Cardiovascular Health Integrated Lifestyle Diet–1) recommendations?

How are pediatric LDL-C levels of 130 mg/dL or higher treated?

How is type I hyperlipoproteinemia (HLP) treated?

How are types IV and V hyperlipoproteinemia (HLP) treated?

How are pediatric hypoalphalipoproteinemia (low HDL-C levels) treated?

How are types IIA and IIB hyperlipoproteinemia (HLP) treated?

What are the NHLBI guidelines on the treatment of type II hyperlipoproteinemia (HLP)?

What are the AHA guidelines on the treatment of type II hyperlipoproteinemia (HLP)?

What is the role of statins in the treatment of pediatric lipid disorders?

What is the role of bile acid-binding resins in the treatment of pediatric lipid disorders?

What is the role of niacin in the treatment of pediatric lipid disorders?

What is the role of fibric acid derivatives in the treatment of pediatric lipid disorders?

What is the role of ezetimibe (Zetia) in the treatment of pediatric lipid disorders?

What is the role of aspirin in the treatment of pediatric lipid disorders?

What is the role of fish oils in the treatment of pediatric lipid disorders?

What is the role of dietary fiber in the treatment of pediatric lipid disorders?

How is homozygous FH treated?

What is the role of medications in the treatment of type I hyperlipoproteinemia (HLP)?

What is the role of medications in the treatment of type III hyperlipoproteinemia (HLP)?

What is the role of medications in the treatment of types IV and V hyperlipoproteinemia (HLP)?

What is the role of medications in the treatment of pediatric hypoalphalipoproteinemia (low HDL-C levels)?

Which medications are used in the treatment of pediatric lipid disorders?

Guidelines

What are the ACC/AHA cholesterol management guidelines for children and adolescents?

Which organization has released guidelines on physical activity for children and adolescents?

What are the USDHHS guidelines on physical activity for children and adolescents?

How does physical activity affect sleep in children and adolescents?

How does physical activity affect disease risk in children and adolescents?

What are effective ways to promote physical activity in children and adolescents?

What are the British Society of Echocardiography and Cardiac Risk in the Young guidelines on cardiac screening for young athletes?