Schatzki Ring Medication

Updated: Dec 16, 2014
  • Author: Rajeev Vasudeva, MD; Chief Editor: Julian Katz, MD  more...
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Medication

Medication Summary

No specific drug therapy for Schatzki ring exists. Consider treating any associated reflux disease with potent antisecretory agents (eg, proton pump inhibitors).

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Proton pump inhibitors

Class Summary

Inhibits H+/K+ -ATPase enzyme system in the gastric parietal cells, resulting in decreased gastric acid secretion. Used for esophagitis or unresponsiveness to H2-antagonist therapy.

Rabeprazole sodium (Aciphex)

Decreases gastric acid secretion by inhibiting the parietal cell H+/K+ ATP pump. For short-term (4-8 wk) treatment and relief symptomatic erosive or ulcerative GERD. Patients not healed after 8 wk, consider additional 8-wk course.

Esomeprazole magnesium (Nexium)

S-isomer of omeprazole. Inhibits gastric acid secretion by inhibiting H+/K+ -ATPase enzyme system at secretory surface of gastric parietal cells.

Omeprazole (Prilosec)

Inhibits gastric acid secretion. Used for the short-term treatment (4-8 wk) of GERD. May be needed for long-term therapy.

Pantoprazole (Protonix)

Suppresses gastric acid secretion by specifically inhibiting H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells.

Lansoprazole (Prevacid)

Inhibits gastric acid secretion. Used for up to 8 wk to treat all grades of erosive esophagitis.

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