Schatzki Ring Medication

Updated: Dec 24, 2020
  • Author: Rajeev Vasudeva, MD; Chief Editor: Julian Katz, MD  more...
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Medication

Medication Summary

No specific drug therapy for Schatzki ring exists. If reflux disease is suspected based on symptoms or endoscopic findings, consider treating with potent antisecretory agents (eg, proton pump inhibitors) in addition to antireflux precautions.

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Proton pump inhibitors

Class Summary

Inhibits H+/K+ -ATPase enzyme system in the gastric parietal cells, resulting in decreased gastric acid secretion. Used for esophagitis or unresponsiveness to H2-antagonist therapy.

Rabeprazole sodium (Aciphex)

Decreases gastric acid secretion by inhibiting the parietal cell H+/K+ ATP pump. For short-term (4-8 wk) treatment and relief symptomatic erosive or ulcerative GERD. Patients not healed after 8 wk, consider additional 8-wk course.

Esomeprazole magnesium (Nexium)

S-isomer of omeprazole. Inhibits gastric acid secretion by inhibiting H+/K+ -ATPase enzyme system at secretory surface of gastric parietal cells.

Omeprazole (Prilosec)

Inhibits gastric acid secretion. Used for the short-term treatment (4-8 wk) of GERD. May be needed for long-term therapy.

Pantoprazole (Protonix)

Suppresses gastric acid secretion by specifically inhibiting H+/K+ ATPase enzyme system at the secretory surface of gastric parietal cells.

Lansoprazole (Prevacid)

Inhibits gastric acid secretion. Used for up to 8 wk to treat all grades of erosive esophagitis.

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