Zollinger-Ellison Syndrome Questions & Answers

Updated: Jan 04, 2019
  • Author: Praveen K Roy, MD, AGAF; Chief Editor: Philip O Katz, MD, FACP, FACG  more...
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Questions & Answers

Overview

What is Zollinger-Ellison syndrome (ZES)?

What is the pathophysiology of Zollinger-Ellison syndrome (ZES)?

What causes Zollinger-Ellison syndrome (ZES)?

What is the prevalence of Zollinger-Ellison syndrome (ZES) in the US?

Which patient groups have the highest prevalence of Zollinger-Ellison syndrome (ZES)?

What is the global prevalence of Zollinger-Ellison syndrome (ZES)?

What is the prognosis of Zollinger-Ellison syndrome (ZES)?

What are the possible complications of Zollinger-Ellison syndrome (ZES)?

Presentation

Which clinical history findings are characteristic of Zollinger-Ellison syndrome (ZES)?

Which physical findings are characteristic of Zollinger-Ellison syndrome (ZES)?

DDX

Which conditions are included in the differential diagnoses of Zollinger-Ellison syndrome (ZES)?

What are the differential diagnoses for Zollinger-Ellison Syndrome?

Workup

Which lab tests are performed in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of fasting serum gastrin levels in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of serum calcium levels in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of gastric acid secretory tests in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of provocative tests in the workup of Zollinger-Ellison syndrome (ZES)?

How is suspected gastrinoma evaluated in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of SRS in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of CT scanning in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of MRI in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of ultrasonography in the workup of Zollinger-Ellison syndrome (ZES)?

What is the role of esophagogastroduodenoscopy in the workup of Zollinger-Ellison syndrome (ZES)?

Treatment

How is Zollinger-Ellison syndrome (ZES) treated?

Which specialist consultations are beneficial to patients with Zollinger-Ellison syndrome (ZES)?

What is the role of surgery in the treatment of Zollinger-Ellison syndrome (ZES)?

What is included in the long-term monitoring of Zollinger-Ellison syndrome (ZES)?

Medications

What is the role of medical therapy in the treatment of Zollinger-Ellison syndrome (ZES)?

Which medications in the drug class Proton pump inhibitors are used in the treatment of Zollinger-Ellison Syndrome?