Wound Infection Questions & Answers

Updated: Jun 11, 2018
  • Author: Hemant Singhal, MD, MBBS, MBA, FRCS(Edin), FRCS, FRCSC; Chief Editor: John Geibel, MD, DSc, MSc, AGAF  more...
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Questions & Answers

Overview

How were physical ailments and wound infections managed in antiquity?

At the start of the first millennium, what were the identifiable manifestations of wound infection?

What is the history of wound infection and management in the 19th century?

How were wound infections treated during the World War era?

What is the pathophysiology of wound healing?

What is the pathophysiology of the inflammatory phase of wound healing?

What is the pathophysiology of the proliferative phase of wound healing?

What is the pathophysiology of the maturation phase of wound healing?

What factors affect wound healing?

Which microbial factors influence the establishment of a wound infection?

What are the causes of surgical site infections (SSIs)?

What are the pathogens commonly associated with wound infections?

What is the role of MRSA in wound infections?

What factors decrease host resistance to wound infections?

What is the prevalence of surgical site infections (SSIs) in the US?

What is the global prevalence of surgical site infections (SSIs)?

What are the morbidity and mortality of surgical site infections (SSIs)?

Presentation

How does the CDC define and classify surgical site infections (SSIs)?

How are superficial surgical site infections (SSIs) characterized?

How are deep incisional surgical site infections (SSIs) characterized?

How are organ surgical site infections (SSIs) characterized?

What are examples of wound infections?

DDX

What are the differential diagnoses for Wound Infection?

Workup

What techniques may be used for identification of wound infections?

What is the role of ultrasonography in the identification of wound infections?

Treatment

How are wound infections managed?

When are prophylactic antibiotics indicated against wound infections?

What are the criteria for the use of systemic antibiotics in surgical procedures for wound infections prevention?

What are recommended prophylactic antibiotics against wound infection?

How and when should antibiotic prophylaxis against wound infection be administered?

What is the current risk index for wound infection assessment?

What is the National Nosocomial Infections Surveillance (NNIS) risk index?

What are some preoperative recommendations to minimize wound infection and surgical site infections (SSIs)?

What are CDC category IA recommendations for preoperative patient preparation to prevent wound infections?

What are CDC category IB recommendations for preoperative patient preparation to prevent wound infections?

What is the CDEC category II recommendation for preoperative patient preparation to prevent wound infections?

Under what circumstances did the CDC make no recommendations for preoperative patient preparation to prevent wound infections?

What are the CDC category IB recommendations for preoperative considerations for surgical team members to prevent wound infection?

What are the CDC category II recommendations for preoperative considerations for surgical team members to prevent wound infection?

Under what circumstances did the CDC make no recommendations for preoperative considerations for surgical team members to prevent wound infection?

What are CDC category IA recommendations for preoperative and postoperative wound care to prevent infection?

What are CDC category IB recommendations for preoperative and postoperative wound care to prevent infection?

What are CDC category II recommendations for preoperative and postoperative wound care to prevent wound infection?

What are CDC category IB recommendations for the operating environment and care of instrumentation to prevent wound infections?

What are CDC category II recommendations for the operating environment and care of instrumentation to prevent wound infections?

What is the role of mechanical cleansing for prevention of wound infection in elective colon surgery?

What are intravascular device-related infections and how are they managed?

How are surgical site infections (SSIs) treated?

What is the role of blood glucose, body temperature and oxygenation in the prevention of wound infections?

What is the role of infection surveillance units in the prevention of surgical site infections (SSIs)?

What strategies can be employed to reduce pathogen resistance in wound infection?

Guidelines

What are the CDC guidelines for prevention of surgical site infection (SSI)?

What are the WHO guidelines for prevention of surgical site infection (SSI)?

What are the IDSA guidelines for prevention of surgical site infection (SSI)?

Medications

What is the basis for antibiotic selection for the treatment of wound infection?

Which medications in the drug class Antibiotics are used in the treatment of Wound Infection?