Plasmapheresis Questions & Answers

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2. [Guideline] Padmanabhan A, Connelly-Smith L, Aqui N, Balogun RA, Klingel R, Meyer E, et al. Guidelines on the Use of Therapeutic Apheresis in Clinical Practice - Evidence-Based Approach from the Writing Committee of the American Society for Apheresis: The Eighth Special Issue. J Clin Apher. 2019 Jun. 34 (3):171-354. [QxMD MEDLINE Link].

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4. Gerhardt RE, Ntoso KA, Koethe JD, Lodge S, Wolf CJ. Acute plasma separation with hemodialysis equipment. J Am Soc Nephrol. 1992 Mar. 2 (9):1455-8. [QxMD MEDLINE Link].

5. Gurland HJ, Lysaght MJ, Samtleben W, Schmidt B. A comparison of centrifugal and membrane-based apheresis formats. Int J Artif Organs. 1984 Jan. 7 (1):35-8. [QxMD MEDLINE Link].

6. Agishi T, Kaneko I, Hasuo Y, Hayasaka Y, Sanaka T, Ota K, et al. Double filtration plasmapheresis. 1980. Ther Apher. 2000 Feb. 4 (1):29-33. [QxMD MEDLINE Link].

7. Siami GA, Siami FS. Current topics on cryofiltration technologies. Ther Apher. 2001 Aug. 5 (4):283-6. [QxMD MEDLINE Link].

8. Malchesky PS. Therapeutic Apheresis: Why?. Ther Apher Dial. 2015 Oct. 19 (5):417-26. [QxMD MEDLINE Link]. [Full Text].

9. Pham HP, Schwartz J, Cooling L, Hofmann JC, Kim HC, Morgan S, et al. Report of the ASFA apheresis registry study on Wilson's disease. J Clin Apher. 2016 Feb. 31 (1):11-5. [QxMD MEDLINE Link].

10. Blechinger S, Ehler J, Bsteh G, Winkelmann A, Leutmezer F, Meister S, et al. Therapeutic plasma exchange in steroid-refractory multiple sclerosis relapses. A retrospective two-center study. Ther Adv Neurol Disord. 2021. 14:1756286420975642. [QxMD MEDLINE Link]. [Full Text].

11. Chang CT, Tsai TY, Liao HY, Chang CM, Jheng JS, Huang WH, et al. Double Filtration Plasma Apheresis Shortens Hospital Admission Duration of Patients With Severe Hypertriglyceridemia-Associated Acute Pancreatitis. Pancreas. 2016 Apr. 45 (4):606-12. [QxMD MEDLINE Link].

12. Chen Z, Huang X, Han N, Guo Y, Chen J, Ning Y, et al. Total cholesterol concentration predicts the effect of plasmapheresis on hypertriglyceridemic acute pancreatitis: a retrospective case-control study. BMC Gastroenterol. 2021 Jan 6. 21 (1):3. [QxMD MEDLINE Link]. [Full Text].

13. Torres VVL, Coggon CF, Wells TJ. Antibody-Dependent Enhancement of Bacterial Disease: Prevalence, Mechanisms, and Treatment. Infect Immun. 2021 Mar 17. 89 (4):e00054-21. [QxMD MEDLINE Link]. [Full Text].

14. Hashemian SM, Shafigh N, Afzal G, Jamaati H, Tabarsi P, Marjani M, et al. Plasmapheresis reduces cytokine and immune cell levels in COVID-19 patients with acute respiratory distress syndrome (ARDS). Pulmonology. 2021 Nov-Dec. 27 (6):486-492. [QxMD MEDLINE Link]. [Full Text].

15. Kamran SM, Mirza ZE, Naseem A, Liaqat J, Fazal I, Alamgir W, et al. Therapeutic plasma exchange for coronavirus disease-2019 triggered cytokine release syndrome; a retrospective propensity matched control study. PLoS One. 2021. 16 (1):e0244853. [QxMD MEDLINE Link]. [Full Text].

16. McLeod BC, Sniecinski I, Ciavarella D, Owen H, Price TH, Randels MJ, et al. Frequency of immediate adverse effects associated with therapeutic apheresis. Transfusion. 1999 Mar. 39 (3):282-8. [QxMD MEDLINE Link].

17. Apter AJ, Kaplan AA. An approach to immunologic reactions associated with plasma exchange. J Allergy Clin Immunol. 1992 Jul. 90 (1):119-24. [QxMD MEDLINE Link].

18. McLeod BC. Therapeutic apheresis: use of human serum albumin, fresh frozen plasma and cryosupernatant plasma in therapeutic plasma exchange. Best Pract Res Clin Haematol. 2006. 19 (1):157-67. [QxMD MEDLINE Link].

19. Silberstein LE, Naryshkin S, Haddad JJ, Strauss JF 3rd. Calcium homeostasis during therapeutic plasma exchange. Transfusion. 1986 Mar-Apr. 26 (2):151-5. [QxMD MEDLINE Link].

20. Krishnan RG, Coulthard MG. Minimising changes in plasma calcium and magnesium concentrations during plasmapheresis. Pediatr Nephrol. 2007 Oct. 22 (10):1763-6. [QxMD MEDLINE Link].

21. Goldstein SL. Therapeutic apheresis in children: special considerations. Semin Dial. 2012 Mar-Apr. 25 (2):165-70. [QxMD MEDLINE Link].

22. Mokrzycki MH, Kaplan AA. Therapeutic plasma exchange: complications and management. Am J Kidney Dis. 1994 Jun. 23 (6):817-27. [QxMD MEDLINE Link].

23. Owen HG, Brecher ME. Atypical reactions associated with use of angiotensin-converting enzyme inhibitors and apheresis. Transfusion. 1994 Oct. 34 (10):891-4. [QxMD MEDLINE Link].

Elliot Stieglitz, MD Pediatric Oncologist, University of California, San Francisco, School of Medicine

Disclosure: Nothing to disclose.

James Huang, MD Clinical Professor of Pediatrics, Director of Pediatric Hematology, University of California, San Francisco, School of Medicine

James Huang, MD is a member of the following medical societies: American Society of Hematology, American Society of Pediatric Hematology/Oncology, Hemophilia and Thrombosis Research Society

Disclosure: Received grant/research funds from Baxter Healthcare Corporation for research; Received grant/research funds from BPL for research.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Emmanuel C Besa, MD Professor Emeritus, Department of Medicine, Division of Hematologic Malignancies and Hematopoietic Stem Cell Transplantation, Kimmel Cancer Center, Jefferson Medical College of Thomas Jefferson University

Emmanuel C Besa, MD is a member of the following medical societies: American Association for Cancer Education, American Society of Clinical Oncology, American College of Clinical Pharmacology, American Federation for Medical Research, American Society of Hematology, New York Academy of Sciences

Disclosure: Nothing to disclose.

Acknowledgments

The authors wish to thank Beth DuVardo, RN, and Lillian Larue, RN, of the Apheresis Unit at University of California, San Francisco, School of Medicine for their assistance with this article.

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