Gardner Syndrome Questions & Answers

Updated: Jul 29, 2020
  • Author: Hemant Singhal, MD, MBBS, MBA, FRCS, FRCS(Edin), FRCSC; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Questions & Answers

Overview

What is Gardner syndrome?

What is the anatomy of the colon relevant to Gardner syndrome?

What is the role of genetics in the pathogenesis of Gardner syndrome?

What causes Gardner syndrome?

What is the prevalence of Gardner syndrome?

What is the prognosis for Gardner syndrome?

What are the goals of patient education about Gardner syndrome?

Presentation

Which clinical history findings are characteristic of Garner syndrome?

What are the signs and symptoms of extracolonic manifestations of Gardner syndrome?

Which physical exam findings are characteristic of Garner syndrome?

Workup

Which lab tests are performed in the workup for Gardner syndrome?

Which imaging studies are performed in the workup of Gardner syndrome?

What is the role of colonoscopy in the workup of Gardner syndrome?

What is the role of esophagogastroduodenoscopy (EGD) in the workup of Gardner syndrome?

What is the role of a slit-lamp exam in the workup of Gardner syndrome?

Treatment

How is Gardner syndrome treated?

When is surgery contraindicated for the treatment of Gardner syndrome?

Which medications are used in the treatment of Gardner syndrome?

What is the role of surgery in the treatment of Gardner syndrome?

What are the surgical options for the treatment of Gardner syndrome?

What is the risk of colorectal cancer following surgical treatment of Gardner syndrome?

How does the surgical treatment of Gardner syndrome affect anal function?

What is the risk for sexual dysfunction following surgical treatment of Gardner syndrome?

How do the complication rates compare between IRA and IPAA for the treatment of Garner syndrome?

What are the possible colonic complications of Gardner syndrome?

What are the possible extracolonic complications of Gardner syndrome?

What is the prevalence of congenital hypertrophy of retinal pigmented epithelium (CHRPE) in patients with Gardner syndrome?

Which dental abnormalities are associated with Gardner syndrome?

How common are osteomas in patients with Gardner syndrome?

What is the prevalence of epidermoid cysts in patients with Gardner syndrome?

What is the prevalence of desmoids in patients with Gardner syndrome?

What are the signs and symptoms of desmoids in patients with Gardner syndrome?

How are desmoids treated in patients with Gardner syndrome?

What is the prevalence of gastric lesions in patients with Gardner syndrome?

What is the prevalence of duodenal polyps in patients with Gardner syndrome?

What are the signs and symptoms of duodenal polyps in patients with Gardner syndrome?

How are duodenal polyps treated in patients with Gardner syndrome?

How does Gardner syndrome affect the risk for thyroid cancer?

Which noncolonic malignancies are associated with Gardner syndrome?

What is included in the long-term monitoring following surgery for Gardner syndrome?