Hyperosmolar Hyperglycemic State Differential Diagnoses

Updated: May 26, 2023
  • Author: Dipa Avichal, DO; Chief Editor: George T Griffing, MD  more...
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Diagnostic Considerations

In addition to the conditions listed in the differential diagnosis, any condition that can cause altered mental status should be considered, including the following [2] :

  • Central nervous system infection
  • Hypoglycemia
  • Hyponatremia
  • Severe dehydration
  • Uremia
  • Hyperammonemia
  • Intoxication (eg, with ethanol, narcotics, other drugs)
  • Sepsis
  • Change in mental status or level of consciousness
  • Postictal state
  • Arrhythmia
  • Hypotension
  • Other causes of dehydration
  • Acute blood loss (gastrointestinal or other)
  • Polyuria
  • Excessive diuretic use

Differential Diagnoses