Guidelines Summary
American Thoracic Society guidelines for exercise-induced bronchoconstriction
The American Thoracic Society has developed new evidence-based practice guidelines for individuals with exercise-induced bronchoconstriction. These guidelines address its diagnosis, management, and environmental triggers, as well as considerations in elite athletes. [21]
The recommendations in managing exercise-induced bronchoconstriction include the following:
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Preexercise administration of an inhaled short-acting beta-agonist (SABA) (about 15 minutes before exercise)
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Use of a daily inhaled corticosteroid, a daily leukotriene receptor antagonist, or a mast cell stabilizing agent before exercise for patients who continue to exhibit symptoms despite administration of SABA therapy or who require daily or more frequent SABA use
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Interval or combination warm-up exercise before planned exercise for all patients with exercise-induced bronchoconstriction
Daily use of an inhaled long-acting beta-agonist (LABA) or an inhaled corticosteroid is not recommended as monotherapy in patients with symptoms despite SABA therapy or in patients who require daily or more frequent SABA use. [21]
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Pathogenesis of asthma. Antigen presentation by the dendritic cell with the lymphocyte and cytokine response leading to airway inflammation and asthma symptoms.
