Benign Tumors of Minor Salivary Glands Differential Diagnoses

1. Spuntarelli G, Santecchia L, Urbani U, Zama M. Minor salivary gland neoplasm in children. J Craniofac Surg. 2013 Mar. 24(2):664-7. [Medline].

2. Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol. 1985 May. 146 (1):51-8. [Medline].

3. Ritwik P, Brannon RB. A clinical analysis of nine new pediatric and adolescent cases of benign minor salivary gland neoplasms and a review of the literature. J Med Case Rep. 2012 Sep 11. 6(1):287. [Medline]. [Full Text].

4. Carlson ER, Schimmele SR. The management of minor salivary gland tumors of the oral cavity. Atlas Oral Maxillofac Surg Clin North Am. 1998 Mar. 6 (1):75-98. [Medline].

5. Califano J, Eisele DW. Benign salivary gland neoplasms. Otolaryngol Clin North Am. 1999 Oct. 32 (5):861-73. [Medline].

6. Batsakis JG, Regezi JA. The pathology of head and neck tumors: salivary glands, part 1. Head Neck Surg. 1978 Sep-Oct. 1 (1):59-68. [Medline].

7. Land CE, Saku T, Hayashi Y, Takahara O, Matsuura H, Tokuoka S, et al. Incidence of salivary gland tumors among atomic bomb survivors, 1950-1987. Evaluation of radiation-related risk. Radiat Res. 1996 Jul. 146 (1):28-36. [Medline].

8. Horn-Ross PL, Ljung BM, Morrow M. Environmental factors and the risk of salivary gland cancer. Epidemiology. 1997 Jul. 8 (4):414-9. [Medline].

9. Johns MM 3rd, Westra WH, Califano JA, Eisele D, Koch WM, Sidransky D. Allelotype of salivary gland tumors. Cancer Res. 1996 Mar 1. 56 (5):1151-4. [Medline].

10. Voz ML, Aström AK, Kas K, Mark J, Stenman G, Van de Ven WJ. The recurrent translocation t(5;8)(p13;q12) in pleomorphic adenomas results in upregulation of PLAG1 gene expression under control of the LIFR promoter. Oncogene. 1998 Mar. 16 (11):1409-16. [Medline].

11. Venkata V, Irulandy P. The frequency and distribution pattern of minor salivary gland tumors in a government dental teaching hospital, Chennai, India. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2011 Jan. 111(1):e32-9. [Medline].

12. Wang XD, Meng LJ, Hou TT, Zheng C, Huang SH. Frequency and distribution pattern of minor salivary gland tumors in a northeastern Chinese population: a retrospective study of 485 patients. J Oral Maxillofac Surg. 2015 Jan. 73 (1):81-91. [Medline].

13. Nag D, Biswas PK, Mandal PK, Bhattacharyya NK, Gautam D, Mukhopadhyay S. Tumours of minor salivary glands--a clinicopathologic study. J Indian Med Assoc. 2012 Aug. 110(8):567-9, 577. [Medline].

14. Pires FR, Pringle GA, de Almeida OP, Chen SY. Intra-oral minor salivary gland tumors: a clinicopathological study of 546 cases. Oral Oncol. 2007 May. 43 (5):463-70. [Medline].

15. Kleinsasser O, Klein HJ. [Basal cell adenoma of the salivary glands]. Arch Klin Exp Ohren Nasen Kehlkopfheilkd. 1967. 189 (3):302-16. [Medline].

16. Seethala RR, Barnes EL. Rare Malignant and Benign Salivary Gland Epithelial Tumors. Surg Pathol Clin. 2011 Dec. 4 (4):1217-72. [Medline].

17. Headington JT, Batsakis JG, Beals TF, Campbell TE, Simmons JL, Stone WD. Membranous basal cell adenoma of parotid gland, dermal cylindromas, and trichoepitheliomas. Comparative histochemistry and ultrastructure. Cancer. 1977 Jun. 39 (6):2460-9. [Medline].

18. Nelson JF, Jacoway JR. Monomorphic adenoma (canalicular type). Report of 29 cases. Cancer. 1973 Jun. 31 (6):1511-3. [Medline].

19. Daley TD, Gardner DG, Smout MS. Canalicular adenoma: not a basal cell adenoma. Oral Surg Oral Med Oral Pathol. 1984 Feb. 57 (2):181-8. [Medline].

20. Rousseau A, Mock D, Dover DG, Jordan RC. Multiple canalicular adenomas: a case report and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Mar. 87 (3):346-50. [Medline].

21. Brandwein M, Huvos A. Laryngeal oncocytic cystadenomas. Eight cases and a literature review. Arch Otolaryngol Head Neck Surg. 1995 Nov. 121 (11):1302-5. [Medline].

22. Ma J, Chan JK, Chow CW, Orell SR. Lymphadenoma: a report of three cases of an uncommon salivary gland neoplasm. Histopathology. 2002 Oct. 41 (4):342-50. [Medline].

23. Miloro M, Kolokythas A. Diagnosis and management of salivary gland disorders. Hupp JR, Ellis E III, Tucker MR, eds. Contemporary Oral and Maxillofacial Surgery. 6th ed. St Louis: Elsevier Mosby; 2014. 394-420.

24. Brandwein MS, Huvos AG. Oncocytic tumors of major salivary glands. A study of 68 cases with follow-up of 44 patients. Am J Surg Pathol. 1991 Jun. 15 (6):514-28. [Medline].

25. Buxton RW, Maxwell JH, French AJ. Surgical treatment of epithelial tumors of the parotid gland. Surg Gynecol Obstet. 1953 Oct. 97(4):401-16. [Medline].

26. Eveson JW, Cawson RA. Salivary gland tumours. A review of 2410 cases with particular reference to histological types, site, age and sex distribution. J Pathol. 1985 May. 146 (1):51-8. [Medline].

27. Pinkston JA, Cole P. Incidence rates of salivary gland tumors: results from a population-based study. Otolaryngol Head Neck Surg. 1999 Jun. 120 (6):834-40. [Medline].

28. Nagao T, Sugano I, Ishida Y, Asoh A, Munakata S, Yamazaki K, et al. Sialolipoma: a report of seven cases of a new variant of salivary gland lipoma. Histopathology. 2001 Jan. 38 (1):30-6. [Medline].

29. Tumors of salivary glands. El-Naggar AK, Chan JKC, Grandis JR, Takata T, Slootweg PJ, eds. WHO Classification of Head and Neck Tumours. 4th ed. Geneva: World Health Organization; 2017. 159-202.

30. Spiro RH. Salivary neoplasms: overview of a 35-year experience with 2,807 patients. Head Neck Surg. 1986 Jan-Feb. 8 (3):177-84. [Medline].

31. Lee YY, Wong KT, King AD, Ahuja AT. Imaging of salivary gland tumours. Eur J Radiol. 2008 Jun. 66 (3):419-36. [Medline].

32. Colella G, Cannavale R, Flamminio F, Foschini MP. Fine-needle aspiration cytology of salivary gland lesions: a systematic review. J Oral Maxillofac Surg. 2010 Sep. 68 (9):2146-53. [Medline].

33. Jayaram G, Verma AK, Sood N, Khurana N. Fine needle aspiration cytology of salivary gland lesions. J Oral Pathol Med. 1994 Jul. 23 (6):256-61. [Medline].

34. Eneroth CM, Franzen S, Zajicek J. Aspiration biopsy of salivary gland tumors. A critical review of 910 biopsies. Acta Cytol. 1967 Nov-Dec. 11(6):470-2. [Medline].

35. Guidelines of the Papanicolaou Society of Cytopathology for fine-needle aspiration procedure and reporting. The Papanicolaou Society of Cytopathology Task Force on Standards of Practice. Diagn Cytopathol. 1997 Oct. 17 (4):239-47. [Medline].

36. Robertson EG, Baxter G. Tumour seeding following percutaneous needle biopsy: the real story!. Clin Radiol. 2011 Nov. 66 (11):1007-14. [Medline].

37. Dardick I, Daley TD, van Nostrand AW. Basal cell adenoma with myoepithelial cell-derived "stroma": a new major salivary gland tumor entity. Head Neck Surg. 1986 Mar-Apr. 8 (4):257-67. [Medline].

38. Schmidt LA, Olsen SH, McHugh JB. Cutaneous adnexal differentiation and stromal metaplasia in palate pleomorphic adenomas: a potential diagnostic pitfall that may be mistaken for malignancy. Am J Surg Pathol. 2010 Aug. 34 (8):1205-10. [Medline].

39. Carlson ER, Schimmele SR. The management of minor salivary gland tumors of the oral cavity. Atlas Oral Maxillofac Surg Clin North Am. 1998 Mar. 6 (1):75-98. [Medline].

40. Scianna JM, Petruzzelli GJ. Contemporary management of tumors of the salivary glands. Curr Oncol Rep. 2007 Mar. 9 (2):134-8. [Medline].

41. Moore BA, Burkey BB, Netterville JL, Butcher RB 2nd, Amedee RG. Surgical management of minor salivary gland neoplasms of the palate. Ochsner J. 2008 Winter. 8 (4):172-80. [Medline].

42. Horowitz G, Ben-Ari O, Wasserzug O, Weizman N, Yehuda M, Fliss DM. The transcervical approach for parapharyngeal space pleomorphic adenomas: indications and technique. PLoS One. 2014. 9 (2):e90210. [Medline].

43. Horn-Ross PL, Morrow M, Ljung BM. Diet and the risk of salivary gland cancer. Am J Epidemiol. 1997 Jul 15. 146 (2):171-6. [Medline].

44. Zheng W, Shu XO, Ji BT, Gao YT. Diet and other risk factors for cancer of the salivary glands:a population-based case-control study. Int J Cancer. 1996 Jul 17. 67 (2):194-8. [Medline].

Vijay A Patel, MD Co-Administrative Chief Resident Physician, Department of Otolaryngology-Head and Neck Surgery, Penn State Health Milton S Hershey Medical Center

Vijay A Patel, MD is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American College of Surgeons, American Rhinologic Society, American Society for Laser Medicine and Surgery, North American Skull Base Society, Pennsylvania Academy of Otolaryngology-Head and Neck Surgery, Pennsylvania Medical Society, The Triological Society

Disclosure: Nothing to disclose.

Tom Shokri, MD Resident Physician, Division of Otolaryngology-Head and Neck Surgery, Penn State Health Milton S Hershey Medical Center

Disclosure: Nothing to disclose.

Neerav Goyal, MD, MPH Assistant Professor of Surgery, Director of Head and Neck Surgery, Division of Otolaryngology-Head and Neck Surgery, Penn State Hershey Medical Center

Neerav Goyal, MD, MPH is a member of the following medical societies: American Academy of Otolaryngology-Head and Neck Surgery, American Head and Neck Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

David L Morris, MD, PhD, FRACS Professor, Department of Surgery, St George Hospital, University of New South Wales, Australia

David L Morris, MD, PhD, FRACS is a member of the following medical societies: British Society of Gastroenterology

Disclosure: Received none from RFA Medical for director; Received none from MRC Biotec for director.

John Geibel, MD, MSc, DSc, AGAF Vice Chair and Professor, Department of Surgery, Section of Gastrointestinal Medicine, Professor, Department of Cellular and Molecular Physiology, Yale University School of Medicine; Director of Surgical Research, Department of Surgery, Yale-New Haven Hospital; American Gastroenterological Association Fellow; Fellow of the Royal Society of Medicine

John Geibel, MD, MSc, DSc, AGAF is a member of the following medical societies: American Gastroenterological Association, American Physiological Society, American Society of Nephrology, Association for Academic Surgery, International Society of Nephrology, New York Academy of Sciences, Society for Surgery of the Alimentary Tract

Disclosure: Nothing to disclose.

Sanjiv S Agarwala, MD Chief of Oncology and Hematology, St Luke's Cancer Center, St Luke's Hospital and Health Network; Professor, Temple University Shool of Medicine

Sanjiv S Agarwala, MD is a member of the following medical societies: American Association for Cancer Research, American Head and Neck Society, European Society for Medical Oncology, American Society of Clinical Oncology, Eastern Cooperative Oncology Group

Disclosure: Received honoraria from BMS for speaking and teaching; Received consulting fee from Novartis for consulting; Received consulting fee from Merck for consulting.

Fadi Chahin, MD Aesthetic and Reconstructive Surgery, Private Practice

Fadi Chahin, MD is a member of the following medical societies: American College of Surgeons, American Society of Plastic Surgeons

Disclosure: Nothing to disclose.

Matthew R Kaufman, MD, FACS Partner, The Institute for Advanced Reconstruction at the Plastic Surgery Center

Matthew R Kaufman, MD, FACS is a member of the following medical societies: Alpha Omega Alpha, American Academy of Otolaryngology-Head and Neck Surgery, American Society of Plastic Surgeons, Phi Beta Kappa

Disclosure: Nothing to disclose.

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