Eosinophilia Differential Diagnoses

Updated: Mar 22, 2023
  • Author: Michaelann Liss, DO; Chief Editor: Emmanuel C Besa, MD  more...
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Diagnostic Considerations

The differential diagnosis of eosinophilia includes the following [22] :

  • Medication reactions
  • Parasitic infestation
  • Asthma/allergy
  • Adrenal insufficiency due to critical illness
  • Multiorgan autoimmune/idiopathic diseases (eg, eosinophilic granulomatosis with polyangiitis)
  • Myeloid neoplasms with eosinophilia
  • Secondary eosinophilia due to lymphoid or epithelial neoplasms
  • Congenital syndromes (ie, hypereosinophilic syndrome, Omenn syndrome, familial eosinophilia)