Overview
What is the pathophysiology of eosinophilia?
What is the pathophysiology of secondary eosinophilia?
What is the role of eosinophilia in the pathophysiology of DRESS syndrome?
What is the pathophysiology of primary eosinophilia?
What is the pathophysiology of eosinophilia in neoplastic disorders?
What is the pathophysiology of hypereosinophilic syndrome (HES)?
What is the role of genetics in the pathophysiology of eosinophilia?
What is the prevalence of eosinophilia in the US?
What is the global prevalence of eosinophilia?
What are the racial predilections of eosinophilia?
What are the sexual predilections of eosinophilia?
Which age group has the highest prevalence of eosinophilia?
What is the prognosis of eosinophilia?
Presentation
What is the focus of the clinical history to evaluate eosinophilia?
What is included in the physical exam to evaluate eosinophilia?
DDX
Which conditions are included in the differential diagnoses of eosinophilia?
Workup
What is the role of lab tests in the workup of eosinophilia?
What is the role of CT scanning in the workup of eosinophilia?
What is the role of echocardiography in the workup of eosinophilia?
What is the role of bone marrow biopsy in the workup of eosinophilia?
What is the role of lumbar puncture in the workup of eosinophilia?
What is the role of urine analysis in the workup of eosinophilia?
Treatment
Which specialist consultations are beneficial to patients with eosinophilia?
Guidelines
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Indurated edematous plaques of hypereosinophilic syndrome on a patient's legs.
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Erythroderma in a patient with hypereosinophilic syndrome.
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Granuloma with a central core of eosinophilic debris surrounded by a peripheral palisade of epithelioid histiocytes and eosinophils from a patient with Churg-Strauss syndrome (allergic granulomatosis).
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Magnified view of papules and nodules with central necrosis in a patient with Churg-Strauss syndrome (allergic granulomatosis).
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High-power photomicrograph of fascia shows heavy inflammatory infiltration with numerous eosinophils, lymphocytes, and occasional plasma cells in a patient with eosinophilic fasciitis.
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Lower back part of the legs in a patient with eosinophilic fasciitis shows hypopigmentation, induration, biopsy site, and asymmetric involvement.
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Egg of Schistosoma hematobium, with its typical terminal spine.