American Joint Committee on Cancer. Malignant Pleural Mesothelioma. Amin MB, Edge S, Greene F, Byrd DR, Brookland RK, et al, eds. AJCC Cancer Staging Manual. 8th ed. New York, NY: Springer; 2017. 457-470.
NCCN Clinical Practice Guidelines in Oncology. Malignant Pleural Mesothelioma. National Comprehensive Cancer Network. Available at https://www.nccn.org/professionals/physician_gls/pdf/mpm.pdf. Version 2.2019 — April 1, 2019; Accessed: October 18, 2019.

Table. TNM Classification for Malignant Pleural Mesothelioma

Primary tumor (T)
TX	Primary tumor cannot be assessed
T0	No evidence of primary tumor
T1	Tumor limited to the ipsilateral parietal pleura with or without mediastinal pleura and with or without involvement of visceral, mediastinal, or diaphragmatic pleura
T2	Tumor involving each of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least 1 of the following: Involvement of the diaphragmatic muscle Extension of tumor from the visceral pleura into the underlying pulmonary parenchyma
T3	Locally advanced but potentially resectable tumor; tumor involving all of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least 1 of the following: Involvement of the endothoracic fascia Extension into the mediastinal fat Solitary, completely resectable focus of tumor extending into the soft tissue of the chest wall Nontransmural involvement of the pericardium
T4	Locally advanced, technically unresectable tumor; tumor involving all of the ipsilateral pleural surfaces (parietal, mediastinal, diaphragmatic, and visceral pleura) with at least 1 of the following: Diffuse extension or multifocal masses of tumor in the chest wall, with or without associated rib destruction Direct diaphragmatic extension of the tumor to the peritoneum Direct extension of the tumor to the contralateral pleura Direct extension of the tumor to a mediastinal organ Direct extension of the tumor into the spine Tumor extending through to the internal surface of the pericardium with or without a pericardial effusion or tumor involving the myocardium
Regional lymph nodes (N)
NX	Regional lymph node(s) cannot be assessed
N0	No regional lymph node metastases
N1	Metastases in the ipsilateral bronchopulmonary, hilar, or mediastinal (including the internal mammary, peridiaphragmatic, pericardial fat pad, or intercostal) lymph nodes
N2	Metastases in the contralateral mediastinal, ipsilateral, or contralateral supraclavicular lymph nodes
Distant metastases (M)
M0	No distant metastasis
M1	Distant metastasis

No Results