Arterial Line Placement Medication

Updated: Sep 21, 2022
  • Author: Sarah Ogle, DO, MS; Chief Editor: Vincent Lopez Rowe, MD, FACS  more...
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Medication Summary

The goal of pharmacotherapy is to provide local anesthesia, both superficial and deep, before and throughout the procedure.



Class Summary

These agents inhibit growth of gram-positive and gram-negative bacteria.

Chlorhexidine gluconate (PerioGard, Peridex, Hibiclens, Avagard)

Chlorhexidine binds to negatively charged bacterial cell walls and extramicrobial complexes. It has bacteriostatic and bactericidal effects.

Povidone-iodine ophthalmic solution 5% (Betadine)

Povidone-iodine is an antibacterial agent with broad antibacterial and antiviral activity. No bacteria are known to be resistant to it.


Local Anesthetics

Class Summary

Local anesthetic agents are used to increase patient comfort during the procedure.

Lidocaine (Xylocaine)

Lidocaine is an amide local anesthetic. This agent inhibits depolarization of type C sensory neurons by blocking sodium channels. It is provided by means of local infiltration of 1% lidocaine buffered with sodium bicarbonate.