Overview
How is erythroleukemia classified?
What is the pathophysiology of erythroleukemia?
What is the prevalence of erythroleukemia?
What is the prognosis of erythroleukemia?
What is included in patient education about erythroleukemia?
Presentation
What are the signs and symptoms of erythroleukemia?
Which physical findings are characteristic of erythroleukemia?
What are the possible complications of erythroleukemia?
DDX
What may complicate the interpretation of bone marrow morphology in erythroleukemia?
What are the differential diagnoses for Erythroleukemia?
Workup
Which tests are performed in the workup of erythroleukemia?
Which blood test findings are characteristic of erythroleukemia?
What is the role of bone marrow biopsy in the workup of erythroleukemia?
What are the WHO diagnostic criteria for pure erythroid leukemia?
What is the role of flow cytometry in the workup of erythroleukemia?
What is the role of cytogenetic analysis in the workup of erythroleukemia?
What is the role of chest radiography in the workup of erythroleukemia?
What is the role of CT and MRI in the workup of erythroleukemia?
What is the role of P-glycoprotein measurement in the workup of erythroleukemia?
What is the role of lumbar puncture in the workup of erythroleukemia?
What is the role of a periodic acid-Schiff (PAS) stain in the workup of erythroleukemia?
When is a pregnancy test and urine cultures indicated in the workup of erythroleukemia?
Treatment
How is erythroleukemia treated?
What is the role of chemotherapy in the treatment of erythroleukemia?
Which dietary modifications are used in the treatment of erythroleukemia?
Which activity modifications are used in the treatment of erythroleukemia?
What is included in the long-term monitoring of erythroleukemia?
Medications
What is the role of medications in the treatment of erythroleukemia?
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Bone marrow aspirate showing erythroblasts in a patient with erythroleukemia. Courtesy of Maurice Barcos, MD, PhD, Department of Pathology, Roswell Park Cancer Institute, Buffalo, NY.