Otitis Externa Organism-Specific Therapy

Updated: Nov 30, 2023
  • Author: Samuel Lee, MD, MS, FACEP; Chief Editor: Michael Stuart Bronze, MD  more...
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Specific Organisms and Therapeutic Regimens

Organism-specific therapeutic regimens for otitis externa are provided below, including those for Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, and Aspergillus niger. Tailor antibiotic therapy based on culture sensitivities. [1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11]

Pseudomonas aeruginosa and Staphylococcus aureus

See the list below:

Pseudomonas aeruginosa (malignant otitis externa)

See the list below:

Fungi (Candida albicans, Aspergillus niger)

See the list below:

  • Clotrimazole 1% otic solution 4 drops in the affected ear QID for 7d (off-label use of topical solution) or

  • Fluconazole 200 mg PO for 1 dose, then 100 mg PO for 3-5d