Specific Organisms and Therapeutic Regimens
Organism-specific therapeutic regimens for acute otitis media in adults are outlined below, including those for Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis, and Pseudomonas aeruginosa. [1, 2, 3, 4, 5, 6, 7, 8, 9]
Streptococcus pneumoniae
See the list below:
-
Amoxicillin 500 mg TID for 7-10d or
-
Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
-
Cefuroxime 500 mg PO BID for 7-14d or
-
Cefpodoxime 200 mg PO BID for 7-10d or
-
Cefprozil 250-500 mg PO BID for 10d or
-
Ceftriaxone 1 g IM every other day for 3 doses or
-
Clindamycin 450 mg PO q6h for 10d
Haemophilus influenzae
See the list below:
-
Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
-
Cefuroxime 500 mg PO BID for 7-14d or
-
Cefpodoxime 200 mg PO BID for 7-10d or
-
Cefprozil 250-500 mg PO BID for 10d or
-
Ceftriaxone 1 g IM every other day for 3 doses
Moraxella catarrhalis
See the list below:
-
Amoxicillin-clavulanate 875 mg/125 mg PO BID for 7-10d or
-
Cefuroxime 500 mg PO BID for 7-14d or
-
Cefpodoxime 200 mg PO BID for 7-10d or
-
Cefprozil 250-500 mg PO BID for 10d or
-
Ceftriaxone 1 g IM every other day for 3 doses
Pseudomonas aeruginosa
See the list below:
-
Vancomycin 0.5-2 g/day PO divided q6-8hr for 7-10 days
