Necrotizing ulcerative gingivitis is a rare disease, a study by Dufty et al finding, for example, a prevalence of 0.11% in the British armed forces.[1, 2] Organism-specific therapeutic regimens for acute necrotizing ulcerative gingivitis (ANUG) are provided below, including those for Peptostreptococci, Prevotella, Bacteroides, and Aggregatibacter actinomycetemcomitans.[3]
See the list below:
Amoxicillin 500 mg PO TID for 10d or
Clindamycin 150-300 mg PO TID for 10d or
Doxycycline 100 mg PO BID for 10d[4]
See the list below:
Amoxicillin 500 mg PO TID for 10d plusmetronidazole 250 mg PO TID for 10d or
Doxycycline 100 mg PO BID for 10d or
Clindamycin 300 mg PO TID for 10d[5]
See the list below:
Saline rinses can help to speed resolution; oral rinses with a hydrogen peroxide 3% solution may be of benefit[6]
Chlorhexidine 0.12% oral rinse 15 mL BID[7]
For human immunodeficiency virus (HIV) ΜΆ positive patients, consider nystatin rinse 5 mL QID orfluconazole 200 mg PO daily for 7-14d
Patients with ANUG should be given a topical anesthetic and nonsteroidal anti-inflammatory drugs (NSAIDs), because pain control is very important in allowing the patient to perform good oral hygiene[8]