Macrocytosis Differential Diagnoses

Updated: Dec 16, 2018
  • Author: Vincent E Herrin, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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DDx

Diagnostic Considerations

Diagnosis of the etiology of macrocytosis is required before the morbidity and mortality can be determined. No complications are directly attributable to the increased size of the red cell; complications are attributed to the condition causing the macrocytosis. Failure to diagnose and treat the cause of the macrocytosis is a medicolegal pitfall. In addition to the conditions listed in the differential diagnosis, liver disease should also be considered.

Differential Diagnoses