Macrocytosis Differential Diagnoses

Updated: Oct 07, 2022
  • Author: Vincent E Herrin, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
  • Print

Diagnostic Considerations

Diagnosis of the etiology of macrocytosis is required to guide treatment and determine the patient's prognosis. No complications are directly attributable to the increased size of the red cell; complications are attributed to the condition causing the macrocytosis. Failure to diagnose and treat the cause of the macrocytosis is a medicolegal pitfall. In addition to the conditions listed in the differential diagnosis, liver disease should also be considered.

Differential Diagnoses