Macrocytosis Medication

Updated: Oct 07, 2022
  • Author: Vincent E Herrin, MD, FACP; Chief Editor: Emmanuel C Besa, MD  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications.



Class Summary

In macrocytosis associated with vitamin deficiencies, the deficient vitamin is replaced to meet necessary dietary requirements. Used in metabolic pathways, DNA and protein synthesis.

Folic acid (Folacin-800)

Folic acid is an important cofactor for enzymes used in the production of red blood cells (RBCs).

Vitamin B-12 (CaloMist, Nascobal, Ener-B)

Deoxyadenosylcobalamin and hydroxocobalamin are active forms of vitamin B-12 in humans. Vitamin B-12 is synthesized by microbes but not by humans or plants. Vitamin B-12 deficiency may result from intrinsic factor deficiency (pernicious anemia), partial or total gastrectomy, or diseases of the distal ileum.

Multivitamins (M.V.I.-12, Infuvite)

Multivitamins are used as dietary supplements.