Xanthogranulomatous Pyelonephritis Differential Diagnoses

Updated: Mar 15, 2021
  • Author: Samuel G Deem, DO; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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DDx

Diagnostic Considerations

Renal cell carcinoma may be indistinguishable from xanthogranulomatous pyelonephritis (XGP) radiographically and clinically. [15] A case of XGP involving thrombus of the renal vein has been reported. [16] XGP and renal cell carcinoma have even been observed in the same specimen.

Shah et al reported a mistaken diagnosis of renal XGP that was subsequently proved to be renal tuberculosis. [17] XGP must be diagnosed on the basis of histologic findings rather than solely on the basis of radiographic imaging studies.