Holoprosencephaly Treatment & Management

Updated: Sep 07, 2017
  • Author: Jay Desai, MD; Chief Editor: Luis O Rohena, MD, FAAP, FACMG  more...
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Medical Care

Medical care is necessary for problems commonly associated with holoprosencephaly, such as seizures, spasticity, choreoathetosis, dystonia, pituitary dysfunction, and gastroesophageal reflux.


Surgical Care

Hydrocephalus, if present, requires neurosurgical intervention with a ventriculoperitoneal shunt. Gastrostomy tube and Nissen fundoplication may be required for feeding difficulties, poor weight gain, and gastroesophageal reflux.