Holoprosencephaly Treatment & Management

Updated: Dec 28, 2020
  • Author: Nusrat Ahsan, MD; Chief Editor: Luis O Rohena, MD, MS, FAAP, FACMG  more...
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Treatment

Medical Care

Medical care is necessary for problems commonly associated with holoprosencephaly, such as seizures, movement disorders, pituitary dysfunction, and gastroesophageal reflux.

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Surgical Care

Neurosurgical intervention may be required if hydrocephalus is present. A gastrostomy tube is needed for feeding difficulties and poor weight gain.

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Prevention

Consistent maternal folic acid use of 400 μg daily, 3 months prior to conception, can be protective. [44, 90]

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