Medical Care

Medical care is necessary for problems commonly associated with holoprosencephaly, such as seizures, movement disorders, pituitary dysfunction, and gastroesophageal reflux.

Surgical Care

Neurosurgical intervention may be required if hydrocephalus is present. A gastrostomy tube is needed for feeding difficulties and poor weight gain.

Prevention

Consistent maternal folic acid use of 400 μg daily, 3 months prior to conception, can be protective.^{[45, 92]}

Medication

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