Secondary Thrombocytosis Clinical Presentation

Updated: Dec 24, 2018
  • Author: Koyamangalath Krishnan, MD, FRCP, FACP; Chief Editor: Srikanth Nagalla, MBBS, MS, FACP  more...
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Presentation

History

No unique symptoms are suggestive of secondary thrombocytosis (reactive thrombocytosis). Most patients are asymptomatic and are identified on routine blood counts. Patients may have symptoms that are referable to the primary condition that may have precipitated the thrombocytosis.

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Physical

No distinguishing features of secondary thrombocytosis (reactive thrombocytosis) are found on physical examination. Physical findings reflect the underlying condition. In patients who have postsplenectomy thrombocytosis, evidence of a previous splenectomy should be eapparent on physical examination. [10]

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Causes

Etiologic conditions associated with secondary thrombocytosis (reactive thrombocytosis) include the following:

  • Infection and inflammatory disorders

  • Postsplenectomy or hyposplenism

  • Malignancy

  • Trauma

  • Chronic inflammatory conditions

  • Hemorrhage, blood loss, or both

  • Iron-deficiency anemia

  • Rebound thrombocytosis

  • Asplenia (anatomic or functional) [14]

  • Electric shock [15]

  • Idiopathic

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