Eucapnic Hyperventilation Laboratory Medicine

1. Fitch KD, Sue-Chu M, Anderson SD, et al. Asthma and the elite athlete: summary of the International Olympic Committee's consensus conference, Lausanne, Switzerland, January 22-24, 2008. J Allergy Clin Immunol. 2008 Aug. 122(2):254-60, 260.e1-7. [Medline]. [Full Text].

2. Chateaubriand do Nascimento Silva Filho MJ, Goncalves AV, Tavares Viana M, Peixoto DM, Cavalcanti Sarinho ES, Rizzo JA. Exercise-induced bronchoconstriction diagnosis in asthmatic children: comparison of treadmill running and eucapnic voluntary hyperventilation challenges. Ann Allergy Asthma Immunol. 2015 Oct. 115(4):277-81. [Medline].

3. Dickinson JW, Whyte GP, McConnell AK, Harries MG. Screening elite winter athletes for exercise induced asthma: a comparison of three challenge methods. Br J Sports Med. 2006 Feb. 40(2):179-82; discussion 179-82. [Medline]. [Full Text].

4. Anderson SD, Fitch K, Perry CP, et al. Responses to bronchial challenge submitted for approval to use inhaled beta2-agonists before an event at the 2002 Winter Olympics. J Allergy Clin Immunol. 2003 Jan. 111(1):45-50. [Medline].

5. Anderson SD, Sue-Chu M, Perry CP, et al. Bronchial challenges in athletes applying to inhale a beta2-agonist at the 2004 Summer Olympics. J Allergy Clin Immunol. 2006 Apr. 117(4):767-73. [Medline]. [Full Text].

6. Anderson SD, Holzer K. Exercise-induced asthma: is it the right diagnosis in elite athletes?. J Allergy Clin Immunol. 2000 Sep. 106(3):419-28. [Medline]. [Full Text].

7. Anderson SD, Daviskas E. The mechanism of exercise-induced asthma is ... J Allergy Clin Immunol. 2000 Sep. 106(3):453-9. [Medline]. [Full Text].

8. Rundell KW, Anderson SD, Spiering BA, Judelson DA. Field exercise vs laboratory eucapnic voluntary hyperventilation to identify airway hyperresponsiveness in elite cold weather athletes. Chest. 2004 Mar. 125(3):909-15. [Medline]. [Full Text].

9. Couillard S, Bougault V, Turmel J, Boulet LP. Perception of bronchoconstriction following methacholine and eucapnic voluntary hyperpnea challenges in elite athletes. Chest. 2014 Apr. 145(4):794-802. [Medline].

10. Phillips YY, Jaeger JJ, Laube BL, Rosenthal RR. Eucapnic voluntary hyperventilation of compressed gas mixture. A simple system for bronchial challenge by respiratory heat loss. Am Rev Respir Dis. 1985 Jan. 131(1):31-35. [Medline]. [Full Text].

11. Kippelen P, Larsson J, Anderson SD, et al. Acute effects of beclomethasone on hyperpnea-induced bronchoconstriction. Med Sci Sports Exerc. 2010 Feb. 42(2):273-80. [Medline]. [Full Text].

12. Brannan JD, Koskela H, Anderson SD, Chew N. Responsiveness to mannitol in asthmatic subjects with exercise- and hyperventilation-induced asthma. Am J Respir Crit Care Med. 1998 Oct. 158(4):1120-6. [Medline].

13. S D Anderson, G J Argyros, H Magnussen, K Holzer. Provocation by eucapnic voluntary hyperpnoea to identify exercise induced bronchoconstriction. Br J Sports Med 2001. 35:5:344-347. [Full Text].

14. Brummel NE, Mastronarde JG, Rittinger D, Philips G, Parsons JP. The clinical utility of eucapnic voluntary hyperventilation testing for the diagnosis of exercise-induced bronchospasm. J Asthma. 2009 Sep. 46(7):683-6. [Medline]. [Full Text].

15. Anderson SD. How does exercise cause asthma attacks?. Curr Opin Allergy Clin Immunol 2006 Feb. 6(1):37-42. [Medline]. [Full Text].

16. Holzer K, Anderson SD, Chan HK, Douglass J. Mannitol as a challenge test to identify exercise-induced bronchoconstriction in elite athletes. Am J Respir Crit Care Med. 2003 Feb 15. 167(4):534-7. [Medline].

17. Sue-Chu M, Brannan JD, Anderson SD, Chew N, Bjermer L. Airway hyperresponsiveness to methacholine, adenosine 5-monophosphate, mannitol, eucapnic voluntary hyperpnoea and field exercise challenge in elite cross-country skiers. Br J Sports Med. 2010 Sep. 44(11):827-32. [Medline]. [Full Text].

18. Mannix ET, Manfredi F, Farber MO. A comparison of two challenge tests for identifying exercise-induced bronchospasm in figure skaters. Chest. 1999 Mar. 115(3):649-53. [Medline]. [Full Text].

19. Davis BJ, Kream RM. Substance P immunoreactivity in the superficial laminae of the hamster olfactory bulb. Neuroreport. 1991 Dec. 2(12):739-42. [Medline]. [Full Text].

Rakesh Vadde, MBBS Fellow in Pulmonary Medicine, Interfaith Medical Center

Rakesh Vadde, MBBS is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Thoracic Society

Disclosure: Nothing to disclose.

M Frances J Schmidt, MD Chief of Pulmonary Medicine, Pulmonary Fellowship Program, Teaching Attending Physician, Department of Medicine, Interfaith Medical Center

M Frances J Schmidt, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians

Disclosure: Nothing to disclose.

Zab Mosenifar, MD, FACP, FCCP Geri and Richard Brawerman Chair in Pulmonary and Critical Care Medicine, Professor and Executive Vice Chairman, Department of Medicine, Medical Director, Women's Guild Lung Institute, Cedars Sinai Medical Center, University of California, Los Angeles, David Geffen School of Medicine

Zab Mosenifar, MD, FACP, FCCP is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Federation for Medical Research, American Thoracic Society

Disclosure: Nothing to disclose.

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