Eucapnic Hyperventilation Periprocedural Care

Updated: Dec 16, 2015
  • Author: Rakesh Vadde, MBBS; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Periprocedural Care


The images below depict eucapnic hyperventilation equipment.

Equipment for Eucapnic Hyperventilation Test Equipment for Eucapnic Hyperventilation Test
Patient undergoing Eucapnic Hyperventilation proce Patient undergoing Eucapnic Hyperventilation procedure


Smoking can interfere with spirometry and eucapnic hyperventilation results by producing false-positive results. If the patient smokes cigarettes or other tobacco products, they must abstain from it for at least 6 hours prior to examination.


Eating and drinking

Patients can eat a normal breakfast or lunch before the procedure; however, they should avoid heavy meal or any alcoholic drinks. Patients should avoid spicy foods and caffeine containing drinks (which may cause heartburn, indigestion, or reflux) on the day of the procedure.


Exercise, cold air

Patient should avoid any strenuous exercise or excess exposure to cold/hot air within 4 hours prior to the test.



Certain medications can interfere with the test results. See the table below.

Table. Medications That Must Be Stopped Prior to Eucapnic Hyperventilation. (Open Table in a new window)

Drug Category Medication Time prior to test
Inhaled bronchodilators Albuterol 8 hours
Ipratropium 24 hours
Salmeterol 48 hours
Oral bronchodilators Long-acting theophylline 48 hours
Inhaled glucocorticoid   2-3 weeks
Oral glucocorticoid   2-3 weeks
Mast cell stabilizers Cromolyn sodium 8 hours
Antihistamines Diphenhydramine 72 hours
Chlorpheniramine 72 hours
Hydroxyzine 72 hours
Cetirizine 72 hours
Leukotriene modifiers Montelukast 24 hours
Zafirlukast 24 hours

Patients are not routinely recommended to withhold inhaled and oral steroid for the test, however its anti-inflammatory effect can affect the bronchial response to the trigger. [11]


Elements of Informed Consent

Patients should be educated about the various steps of the procedure. Patient should be aware of the possible complications of test includes asthmalike symptoms, which include chest tightness, cough, and shortness of breath. These complications can be reversed with an inhaled short-acting bronchodilator.