Bronchial Thermoplasty Questions & Answers

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13. Singh SK, Tiwari KK. Bronchial thermoplasty: a non-pharmacological approach. Clin Respir J. 2015 Apr 27. 35 (6):655-70. [Medline]. [Full Text].

14. Cangelosi MJ, Ortendahl JD, Meckley LM, Bentley TG, Anene AM, Shriner KM, et al. Cost-effectiveness of bronchial thermoplasty in commercially-insured patients with poorly controlled, severe, persistent asthma. Expert Rev Pharmacoecon Outcomes Res. 2015 Apr. 15 (2):357-64. [Medline]. [Full Text].

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17. Blaiss MS, Castro M, Chipps BE, Zitt M, Panettieri RA Jr, Foggs MB. Guiding principles for use of newer biologics and bronchial thermoplasty for patients with severe asthma. Ann Allergy Asthma Immunol. 2017 Dec. 119 (6):533-540. [Medline].

18. Gordon IO, Husain AN, Charbeneau J, Krishnan JA, Hogarth DK. Endobronchial biopsy: a guide for asthma therapy selection in the era of bronchial thermoplasty. J Asthma. 2013 Aug. 50 (6):634-41. [Medline]. [Full Text].

19. Andrychiewicz A, Gorka K, Reid M, Soja J, Sladek K, Szczeklik W. Modern methods for the endoscopic treatment of obstructive pulmonary diseases. J Asthma. 2015 Jan 13. 50 (6):1-19. [Medline]. [Full Text].

20. Cox G, Miller JD, McWilliams A, Fitzgerald JM, Lam S. Bronchial thermoplasty for asthma. Am J Respir Crit Care Med. 2006 May 1. 173 (9):965-9. [Medline]. [Full Text].

21. Castro M, Rubin AS, Laviolette M,et. al. Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med. 2010 Jan 15. 181 (2):116-24. [Medline]. [Full Text].

22. Pavord ID, Cox G, Thomson NC, Rubin AS, Corris PA, Niven RM, et al. Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med. 2007 Dec 15. 176 (12):1185-91. [Medline]. [Full Text].

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25. Miller JD, Cox G, Vincic L, Lombard CM, Loomas BE, Danek CJ. A prospective feasibility study of bronchial thermoplasty in the human airway. Chest. 2005 Jun. 127 (6):1999-2006. [Medline]. [Full Text].

26. Woodruff PG, Dolganov GM, Ferrando RE, Donnelly S, Hays SR, Solberg OD, et al. Hyperplasia of smooth muscle in mild to moderate asthma without changes in cell size or gene expression. Am J Respir Crit Care Med. 2004 May 1. 169 (9):1001-6. [Medline]. [Full Text].

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30. Janssen LJ. Airway smooth muscle as a target in asthma and the beneficial effects of bronchial thermoplasty. J Allergy (Cairo). 2012. 2012:593784. [Medline]. [Full Text].

31. Dyrda P, Tazzeo T, DoHarris L, Nilius B, Roman HN, Lauzon AM, et al. Acute response of airway muscle to extreme temperature includes disruption of actin-myosin interaction. Am J Respir Cell Mol Biol. 2011 Feb. 44 (2):213-21. [Medline]. [Full Text].

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37. Fang L, Li J, Papakonstantinou E, Karakioulaki M, Sun Q, Schumann D, et al. Secreted heat shock proteins control airway remodeling: Evidence from bronchial thermoplasty. J Allergy Clin Immunol. 2021 Mar 3. [Medline].

38. Chaudhuri R, Rubin A, Sumino K, Lapa E Silva JR, Niven R, Siddiqui S, et al. Safety and effectiveness of bronchial thermoplasty after 10 years in patients with persistent asthma (BT10+): a follow-up of three randomised controlled trials. Lancet Respir Med. 2021 Jan 29. [Medline].

39. Kirby M, Ohtani K, Lopez Lisbona RM, Lee AM, Zhang W, et al. Bronchial thermoplasty in asthma: 2-year follow-up using optical coherence tomography. Eur Respir J. 2015 May 28. 50 (7):799-801. [Medline]. [Full Text].

40. Bonta PI, d'Hooghe J, Sterk PJ, Bel EH, Annema JT. Reduction of airway smooth muscle mass after bronchial thermoplasty: are we there yet?. Am J Respir Crit Care Med. 2015 May 15. 191 (10):1207-8. [Medline]. [Full Text].

41. Aubier M, Pretolani M, Chanez P, Thabut G, Debray MP, Taille C, et al. Reply: reduction of airway smooth muscle mass by bronchial thermoplasty in patients with severe asthma. Am J Respir Crit Care Med. 2015 May 15. 191 (10):1208-9. [Medline]. [Full Text].

42. Zanon M, Strieder DL, Rubin AS, Watte G, Marchiori E, Cardoso PFG, et al. Use of MDCT to Assess the Results of Bronchial Thermoplasty. AJR Am J Roentgenol. 2017 Oct. 209 (4):752-756. [Medline].

43. Thomen RP, Sheshadri A, Quirk JD, Kozlowski J, Ellison HD, Szczesniak RD, et al. Regional ventilation changes in severe asthma after bronchial thermoplasty with (3)He MR imaging and CT. Radiology. 2015 Jan. 274 (1):250-9. [Medline]. [Full Text].

44. Gudmundsson G, Gross TJ. Middle lobe syndrome. Am Fam Physician. 1996 Jun. 53 (8):2547-50. [Medline]. [Full Text].

45. Facciolongo N, Menzella F, Lusuardi M, Piro R, Galeone C, Castagnetti C, et al. Recurrent lung atelectasis from fibrin plugs as a very early complication of bronchial thermoplasty: a case report. Multidiscip Respir Med. 2015. 10 (1):9. [Medline]. [Full Text].

46. Balu A, Ryan D, Niven R. Lung abscess as a complication of bronchial thermoplasty. J Asthma. 2015 Mar 13. 2012:1-3. [Medline]. [Full Text].

47. d'Hooghe JNS, van den Berk IAH, Annema JT, Bonta PI. Acute Radiological Abnormalities after Bronchial Thermoplasty: A Prospective Cohort Trial. Respiration. 2017. 94 (3):258-262. [Medline]. [Full Text].

Said A Chaaban, MD Fellow in Pulmonary and Critical Care Medicine, Department of Internal Medicine, Henry Ford Health Systems

Disclosure: Nothing to disclose.

Javier I Diaz-Mendoza, MD Associate Professor of Medicine, Wayne State University School of Medicine; Program Director, Interventional Pulmonology Fellowship, Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital

Javier I Diaz-Mendoza, MD is a member of the following medical societies: American Association for Bronchology and Interventional Pulmonology, American College of Chest Physicians, American Thoracic Society

Disclosure: Nothing to disclose.

Zab Mosenifar, MD, FACP, FCCP Geri and Richard Brawerman Chair in Pulmonary and Critical Care Medicine, Professor and Executive Vice Chairman, Department of Medicine, Medical Director, Women's Guild Lung Institute, Cedars Sinai Medical Center, University of California, Los Angeles, David Geffen School of Medicine

Zab Mosenifar, MD, FACP, FCCP is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Federation for Medical Research, American Thoracic Society

Disclosure: Nothing to disclose.

Mahmoud Mahafzah, MBBS Fellow in Pulmonary and Critical Care Medicine, Center for Lung Health, Henry Ford Hospital

Mahmoud Mahafzah, MBBS is a member of the following medical societies: American Thoracic Society

Disclosure: Nothing to disclose.

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