Factor VII Deficiency Follow-up

Updated: Jul 18, 2017
  • Author: Muhammad A Mir, MD, FACP; Chief Editor: Perumal Thiagarajan, MD  more...
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Follow-up

Further Outpatient Care

Perform annual history and physical examinations and test for hepatitis virus and HIV. Order MRI or CT scans for follow-up of joint deformities. Regular screening tests include cholesterol, prostate-specific antigen levels, colonoscopy, and mammography. In addition, vaccination for hepatitis A and B viruses, dental care, orthopedic follow-up, and patient education are recommended.

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Complications

Infectious complications from transfusion of plasma or factor concentrates include HIV infection and hepatitis. Transmission of other infectious disease is always a theoretical possibility (eg, variant Creutzfeldt-Jakob disease). Recurrent hemarthrosis leads to joint deformities and disability. Occupational and social rehabilitation is necessary.

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Prognosis

Recombinant agent therapy and early intervention of joint disease may result in improved outcomes, as in persons with hemophilia A.

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Patient Education

Patients and family members should be educated about the disease and its transmission. Genetic counseling is recommended. Advise patients to seek medical attention early during the development of symptoms, to consult with specialists, and to comply with follow-up requirements.

For excellent patient education resources, see eMedicineHealth's patient education article Hemophilia.

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