Factor VII Deficiency Questions & Answers

Updated: Aug 06, 2019
  • Author: Muhammad A Mir, MD, FACP; Chief Editor: Perumal Thiagarajan, MD  more...
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Questions & Answers

Overview

What is factor VII deficiency?

What is the role of protein structure to the pathophysiology of factor VII deficiency?

What are the physiologic properties of factor VII?

What is the role of activation in the pathophysiology of factor VII deficiency?

What is the role of coagulation pathways in the pathophysiology of factor VII deficiency?

What is the pathophysiology of factor VII deficiency?

What is the association with thrombotic disease and factor VII deficiency?

What is the mortality and morbidity associated with factor VII deficiency?

What is the global prevalence of factor VII deficiency?

What are the racial predilections of factor VII deficiency?

What are the sexual predilections of factor VII deficiency?

Which age groups have the highest prevalence of factor VII deficiency?

What is the prognosis of factor VII deficiency?

What is included in patient education about factor VII deficiency?

Presentation

Which clinical history findings are characteristic of factor VII deficiency?

Which physical findings are characteristic of factor VII deficiency?

DDX

Which conditions are included in the differential diagnoses of factor VII deficiency?

What are the differential diagnoses for Factor VII Deficiency?

Workup

What is the role of lab tests in the workup of factor VII deficiency?

How is the diagnosis of factor VII deficiency confirmed?

What is the role of imaging studies in the workup of factor VII deficiency?

Treatment

How is factor VII deficiency treated?

What is the role of recombinant factor VIIa (rFVIIa) in the treatment of factor VII deficiency?

What is the role of surgery in the treatment of factor VII deficiency?

Which specialist consultations are beneficial to patients with factor VII deficiency?

Which dietary modifications are used in the treatment of factor VII deficiency?

Which activity modifications are used in the treatment of factor VII deficiency?

What are the possible complications of factor VII deficiency?

What is included in the long-term monitoring of factor VII deficiency?

Medications

Which medications are used in the treatment of factor VII deficiency?

Which medications in the drug class Antifibrinolytic agents are used in the treatment of Factor VII Deficiency?

Which medications in the drug class Blood products are used in the treatment of Factor VII Deficiency?

Which medications in the drug class Antihemophilic agents, drug-product derivatives are used in the treatment of Factor VII Deficiency?