Kikuchi Disease Medication

Updated: Aug 12, 2017
  • Author: John Boone, MD; Chief Editor: Koyamangalath Krishnan, MD, FRCP, FACP  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and to prevent complications. Nonsteroidal anti-inflammatory drugs (NSAIDs) and corticosteroids are most often employed. Hydroxychloroquine has been used in steroid-resistant and recurrent cases.

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Corticosteroids

Class Summary

Corticosteroids have anti-inflammatory properties and cause profound and varied metabolic effects. These agents modify the immune response to diverse stimuli.

Prednisone (Deltasone, Meticorten, Orasone, Sterapred)

May decrease inflammation by reversing increased capillary permeability and suppressing PMN activity.

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Immunosuppressants

Hydroxychloroquine

Mechanism of action unknown; may impair complement-dependent antigen-antibody reactions; inhibits locomotion of neutrophils and chemotaxis of eosinophils

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