Hysterosalpingogram Medication

Updated: Nov 29, 2016
  • Author: Ryan G Steward, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to provide local analgesia and prevent infections.

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Local Anesthetics, Amides

Class Summary

Local anesthetics are used for local pain relief.

Lidocaine (Xylocaine)

Lidocaine is an amide local anesthetic used in 1% concentration. Administration of 10 mL of 1% lidocaine injected into the uterine cavity before the contrast may reduce delayed pain. The 1% preparation contains 10 mg of lidocaine for each 1 mL of solution; Lidocaine inhibits depolarization of type-C sensory neurons by blocking sodium channels.

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Tetracyclines

Class Summary

Empiric antimicrobial therapy must be comprehensive and should cover all likely pathogens in the context of the clinical setting. The American College of Obstetricians and Gynecologists recommends empiric treatment for women with a history of pelvic infection or when hydrosalpinx is diagnosed at the time of the study.

Doxycycline (Doryx, Adoxa, Ocudox, Vibramycin, Oraxyl)

Doxycycline is a broad-spectrum, synthetically derived bacteriostatic antibiotic in the tetracycline class. It is almost completely absorbed, concentrates in bile, and is excreted in urine and feces as a biologically active metabolite in high concentrations.

Doxycycline inhibits protein synthesis and, thus, bacterial growth by binding to 30S and possibly the 50S ribosomal subunits of susceptible bacteria. It may block dissociation of peptidyl t-RNA from ribosomes, causing RNA-dependent protein synthesis to arrest. A common and effective regimen is 100 mg orally twice daily for 5 days.

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