Petrosal Sinus Sampling Periprocedural Care

Updated: Oct 21, 2022
  • Author: Gauri Mankekar, MD, PhD; Chief Editor: Jonathan P Miller, MD  more...
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Periprocedural Care

Pre-Procedure Planning

Inferior petrosal sinus sampling (IPSS) involves a team of radiology and laboratory technicians to interventional radiologists, endocrinologists, nurses, and anesthetists. Miller and Doppman have emphasized teamwork during the procedure with each member of the team performing their role. [19]



In addition to the microcatheters and other interventional radiology equipment, labeled red Vacutainers, EDTA Vacutainers, syringes, oCRH, hCRH, and heparin for infusion should be kept ready and rechecked prior to the start of the procedure.


Patient Preparation

If the patient is receiving aspirin, clopidogrel, metyrapone, and/or ketoconazole, these medications should be discontinued at least 5-7 days before the procedure, with prior consent of the physician who prescribed them.

The patient’s coagulation profile, full blood cell count, blood urea, and electrolytes are checked a day prior to the procedure.

The patient’s blood type is checked, and blood is saved in case a blood transfusion is required during the procedure.

The patient should be kept fasting for at least 4 hours prior to the procedure.

The patient’s groin should be shaved and prepared.


Monitoring & Follow-up

The patient is cautioned against moving his or her limbs for a few hours after the procedure and is prescribed analgesics, if required.