Bladder Stones Medication

Updated: Feb 04, 2020
  • Author: Joseph Basler, MD, PhD; Chief Editor: Bradley Fields Schwartz, DO, FACS  more...
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Medication Summary

The goals of pharmacotherapy are to dissolve the stone, reduce morbidity, and prevent complications. In patients with uric acid stones, urinary alkalinization may help dissolve the stone.


Urinary Alkalinizing Agents

Class Summary

The only potentially effective medical treatment for bladder calculi is urinary alkalization for the dissolution of uric acid stones. However, overly aggressive alkalization may lead to calcium phosphate deposits on the stone surface, making further medical therapy ineffective. [10]

Potassium citrate (Urocit K)

Stone dissolution may be possible if the urinary pH can be made greater than or equal to 6.5. Potassium citrate 60 mEq/day is the treatment of choice.