Exocrine Pancreatic Insufficiency Questions & Answers

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26. Vujasinovic M, Dugic A, Thiel T, Kjellman A, Yang C, Lohr JM. Pancreatic exocrine insufficiency is a risk factor for kidney stones in patients with chronic pancreatitis. Pancreatology. 2023 Apr. 23 (3):294-8. [QxMD MEDLINE Link].

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33. Gonzalez-Sanchez V, Amrani R, Gonzalez V, Trigo C, Pico A, de-Madaria E. Diagnosis of exocrine pancreatic insufficiency in chronic pancreatitis: ¹³C-Mixed Triglyceride Breath Test versus Fecal Elastase. Pancreatology. 2017 Mar 6. [QxMD MEDLINE Link].

34. Saad M, Vitale DS, Lin TK, et al. Image or scope: magnetic resonance imaging and endoscopic testing for exocrine and endocrine pancreatic insufficiency in children. Pancreatology. 2023 Apr 16. [QxMD MEDLINE Link].

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36. Fieker A, Philpott J, Armand M. Enzyme replacement therapy for pancreatic insufficiency: present and future. Clin Exp Gastroenterol. 2011. 4:55-73. [QxMD MEDLINE Link]. [Full Text].

37. Dominguez-Munoz JE. Pancreatic enzyme replacement therapy for pancreatic exocrine insufficiency: when is it indicated, what is the goal and how to do it?. Adv Med Sci. 2011. 56(1):1-5. [QxMD MEDLINE Link].

38. de la Iglesia-Garcia D, Huang W, Szatmary P, et al. Efficacy of pancreatic enzyme replacement therapy in chronic pancreatitis: systematic review and meta-analysis. Gut. 2016 Dec 9. [QxMD MEDLINE Link]. [Full Text].

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40. Whitcomb DC, Lehman GA, Vasileva G, et al. Pancrelipase delayed-release capsules (CREON) for exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery: A double-blind randomized trial. Am J Gastroenterol. 2010 Oct. 105(10):2276-86. [QxMD MEDLINE Link].

41. Gubergrits N, Malecka-Panas E, Lehman GA, Vasileva G, Shen Y, Sander-Struckmeier S, et al. A 6-month, open-label clinical trial of pancrelipase delayed-release capsules (Creon) in patients with exocrine pancreatic insufficiency due to chronic pancreatitis or pancreatic surgery. Aliment Pharmacol Ther. 2011 May. 33(10):1152-61. [QxMD MEDLINE Link].

42. Toskes PP, Secci A, Thieroff-Ekerdt R. Efficacy of a novel pancreatic enzyme product, EUR-1008 (Zenpep), in patients with exocrine pancreatic insufficiency due to chronic pancreatitis. Pancreas. 2011 Apr. 40(3):376-82. [QxMD MEDLINE Link].

43. Trapnell BC, Strausbaugh SD, Woo MS, et al. Efficacy and safety of PANCREAZE® for treatment of exocrine pancreatic insufficiency due to cystic fibrosis. J Cyst Fibros. 2011 Sep. 10(5):350-6. [QxMD MEDLINE Link].

44. Jablonska B. Is endoscopic therapy the treatment of choice in all patients with chronic pancreatitis?. World J Gastroenterol. 2013 Jan 7. 19(1):12-6. [QxMD MEDLINE Link]. [Full Text].

45. Borowitz D, Stevens C, Brettman LR, Campion M, Wilschanski M, Thompson H. Liprotamase long-term safety and support of nutritional status in pancreatic-insufficient cystic fibrosis. J Pediatr Gastroenterol Nutr. 2012 Feb. 54(2):248-57. [QxMD MEDLINE Link].

46. Phillips ME, Hopper AD, Leeds JS, et al. Consensus for the management of pancreatic exocrine insufficiency: UK practical guidelines. BMJ Open Gastroenterol. 2021 Jun. 8 (1):[QxMD MEDLINE Link].

47. Karnik NP, Jan A. Pancrelipase. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].

48. Venkatesh P, Kasi A. Pancrelipase Therapy. 2020 Jan. [QxMD MEDLINE Link]. [Full Text].

Samer Al-Kaade, MD Physician, Mercy Clinic Gastroenterology

Samer Al-Kaade, MD is a member of the following medical societies: American College of Gastroenterology, American Gastroenterological Association, American Pancreatic Association

Disclosure: Serve(d) as a speaker or a member of a speakers bureau for: Abbvie.

Romesh Khardori, MD, PhD, FACP (Retired) Professor, Division of Endocrinology, Diabetes and Metabolism, Department of Internal Medicine, Eastern Virginia Medical School

Romesh Khardori, MD, PhD, FACP is a member of the following medical societies: American Association of Clinical Endocrinologists, American College of Physicians, American Diabetes Association, Endocrine Society

Disclosure: Nothing to disclose.

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