Botulinum Toxin for Laryngeal Dystonia Periprocedural Care

Updated: Nov 02, 2021
  • Author: Jayita Poduval, MS, MBBS, DNB(ENT), DORL; Chief Editor: Arlen D Meyers, MD, MBA  more...
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Periprocedural Care

Pre-Procedure Planning


Botulinum toxin treatment of laryngeal dystonias involves the following:

  • Flexible fiberoptic laryngoscope with distal chip for a two-person approach or a rigid 70° telescope for a one-person approach [4]

  • C-mount camera

  • Video monitor for visualization

  • Curved Abraham canula for delivery of topical lidocaine and vocal fold palpation

  • Needles for percutaneous injection (1.5 inch and 23, 25, or 27 gauge)

  • Flexible fine-gauge injection needle for use with working channel in flexible laryngoscope

  • Electromyographic (EMG) device

Along with the botulinum toxin to be injected, an assortment of syringes and needles, topical and infiltration anesthesia, ground and reference electrodes, alcohol swabs, cotton pledgets, and orotracheal injection device (when necessary) may be needed. [4]


Patient Preparation


Percutaneous electromyography (EMG)–guided botulinum toxin for laryngeal dystonia: Local anaesthesia is optional.

Percutaneous indirect laryngoscopy-guided botulinum toxin for laryngeal dystonia: The cricothyroid membrane is punctured for administration of local anesthesia, instilling approximately 3 mL of 4% lidocaine into the airway.


The patient is positioned in semirecumbent position with the chin elevated and head extended.


Monitoring & Follow-up

Late Sequelae

Late sequelae of botulinum toxin treatment of laryngeal dystonia may include the following:

  • Denervation atrophy

  • Fibrosis

  • EMG changes

Side Effects

Side effects may include the following:

  • Breathy dysphonia

  • Hoarseness

  • Swallowing difficulties (including aspiration)

  • Pain

  • Flulike symptoms


Complications may include the following:

  • Dysphagia

  • Airway compromise

  • Generalized weakness