Cytomegalovirus (CMV) Questions & Answers

Updated: May 05, 2018
  • Author: Kauser Akhter, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Questions & Answers

Overview

What is cytomegalovirus (CMV)?

What are the signs and symptoms of cytomegalovirus (CMV)?

What are clinical manifestations of cytomegalovirus (CMV)?

How is cytomegalovirus (CMV) infection detected?

What is the role of imaging studies in the diagnosis of cytomegalovirus (CMV)?

What are the treatment options for cytomegalovirus (CMV)?

What is cytomegalovirus (CMV)?

What is the prevalence of cytomegalovirus (CMV) infection?

What is the progression of cytomegalovirus (CMV) infection?

How is cytomegalovirus (CMV) infection transmitted?

What is the pathophysiology of cytomegalovirus (CMV) infection?

What is the primary cytomegalovirus (CMV) infection?

What is the role of cell-mediated immunity in the control of cytomegalovirus (CMV) infection?

What is the pathophysiology of primary cytomegalovirus (CMV) infection and viremia?

What is the pathophysiology of congenital cytomegalovirus (CMV) infection?

What is the pathophysiology of cytomegalovirus (CMV) pneumonia?

What is the pathophysiology of cytomegalovirus (CMV) hepatitis?

What is the pathophysiology of cytomegalovirus (CMV) gastritis and colitis?

What is the pathophysiology of cytomegalovirus (CMV) CNS disease?

What is the pathophysiology of cytomegalovirus (CMV) retinitis?

What is the pathophysiology of cytomegalovirus (CMV) nephritis?

What is cytomegalovirus (CMV) syndrome?

What is the role of cytomegalovirus (CMV) infection in the pathophysiology of graft versus host disease?

What is the prevalence of cytomegalovirus (CMV) infection?

What is the mortality and morbidity of cytomegalovirus (CMV)?

How does the prevalence of cytomegalovirus (CMV) vary by age?

What is the prognosis of cytomegalovirus (CMV) infection?

Where can patient education resources for cytomegalovirus (CMV) be found?

Presentation

Which sites are most commonly affected by cytomegalovirus (CMV) infection in the immunocompetent host?

What are the signs and symptoms of cytomegalovirus (CMV) infection in the immunocompetent host?

What are the signs and symptoms of cytomegalovirus (CMV) mononucleosis and how is it differentiated from Epstein-Barr virus (EBV) infectious mononucleosis?

What are risk factors for cytomegalovirus (CMV) mononucleosis?

What are rare manifestations of cytomegalovirus (CMV) infection in the immunocompetent host?

What are the signs and symptoms of cytomegalovirus (CMV) infection in transplant recipients and how does it affect prognosis?

Which organ transplant recipients are at highest risk for cytomegalovirus disease?

Which organ transplant recipients are at highest risk for cytomegalovirus (CMV) pneumonia?

What are the signs and symptoms of CMV pneumonia in organ transplant recipients?

What are the treatment options for CMV pneumonia in organ transplant recipients?

What causes severe cytomegalovirus (CMV) pneumonia in organ transplant recipients and how is it diagnosed?

How is GI cytomegalovirus (CMV) disease managed in organ transplant recipients?

How frequently is cytomegalovirus (CMV) pneumonia comorbid with other pathogens in patients with HIV disease?

What is the manifestation of cytomegalovirus (CMV) GI disease in patients with HIV disease and how is it diagnosed?

What are the clinical manifestations of cytomegalovirus (CMV) retinitis and how is it diagnosed and treated?

Which physical findings are characteristic of cytomegalovirus (CMV) infection?

What are the causes of cytomegalovirus (CMV)?

What causes relapse of cytomegalovirus (CMV) in solid organ transplant recipients?

DDX

What are the differential diagnoses for Cytomegalovirus (CMV)?

Workup

What is the role of lab studies in the workup of cytomegalovirus (CMV) infection?

What is the role of antigen testing in the workup of cytomegalovirus (CMV) infection?

What is the role of qualitative polymerase chain reaction (PCR) in the workup of cytomegalovirus (CMV) infection?

What is the role of quantitative polymerase chain reaction (PCR) in the workup of cytomegalovirus (CMV) infection?

What is the role of shell vial assay in the workup of cytomegalovirus (CMV) infection?

What is the role of cytopathology in the workup of cytomegalovirus (CMV infection)?

What is the role of imaging studies in the workup of cytomegalovirus (CMV) infection?

What is the role of cytomegalovirus antiviral resistance testing in the workup of cytomegalovirus (CMV)?

Which histologic findings indicate cytomegalovirus (CMV)?

Treatment

What is the role of leflunomide in the treatment of cytomegalovirus (CMV)?

Which medications are used in the management of cytomegalovirus (CMV) disease?

What is the role of ganciclovir in the treatment of cytomegalovirus (CMV) disease?

What are the adverse effects of ganciclovir therapy for treatment of cytomegalovirus (CMV) disease?

What is the efficacy of oral valganciclovir in the treatment of cytomegalovirus (CMV) retinitis?

What are the treatment options for cytomegalovirus (CMV) pneumonia?

What is the role of ganciclovir in the treatment of GI and CNS manifestations of cytomegalovirus (CMV)?

What is the role of valganciclovir in the treatment of cytomegalovirus (CMV)?

What is the role of ganciclovir in prophylaxis against cytomegalovirus (CMV) disease?

What is the efficacy of preemptive therapy against cytomegalovirus (CMV) disease?

What is the efficacy of prophylactic approaches against cytomegalovirus (CMV) disease?

What is the role of letermovir for prophylaxis against cytomegalovirus (CMV) disease?

What is the role of foscarnet in the treatment of cytomegalovirus (CMV)?

What is the role of acyclovir in the prophylaxis against cytomegalovirus (CMV) disease?

What is the role of cidofovir in the prophylaxis against cytomegalovirus (CMV) disease?

What is the role of maribavir in the treatment of cytomegalovirus (CMV)?

What is the role of cytomegalovirus immune globulin in the treatment of cytomegalovirus (CMV)?

What is the benefit of consultation with an infectious diseases specialist for the treatment of cytomegalovirus (CMV)?

When is consultation with a hematologist indicated in the treatment of cytomegalovirus (CMV)?

When is consultation with a neurologist indicated in the treatment of cytomegalovirus (CMV)?

When is consultations with an ophthalmologist indicated in the treatment of cytomegalovirus (CMV)?

What activity modifications are indicated in the management of cytomegalovirus (CMV) infection?

How is cytomegalovirus (CMV) prevented?

What is included in outpatient monitoring of patients taking ganciclovir for the treatment of cytomegalovirus (CMV)?

What is included in inpatient care for cytomegalovirus (CMV) disease?

Medications

What are the goals of drug treatment for cytomegalovirus (CMV) infection, and which agents are under investigation for the treatment of CMV disease?

Which medications in the drug class Antimetabolite are used in the treatment of Cytomegalovirus (CMV)?

Which medications in the drug class Immune Globulin are used in the treatment of Cytomegalovirus (CMV)?

Which medications in the drug class Antivirals are used in the treatment of Cytomegalovirus (CMV)?