Dipylidiasis Medication

Updated: Nov 25, 2015
  • Author: Venkat R Minnaganti, MD, FACP; Chief Editor: Michael Stuart Bronze, MD  more...
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Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity, to prevent complications, and to eradicate infection.

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Anthelmintics

Class Summary

Dipylidiasis responds well to treatment with anthelmintics. Praziquantel and niclosamide are the preferred drugs and are usually administered as a single oral dose. A follow-up dose is usually unnecessary.

Praziquantel (Biltricide)

Broad-spectrum anthelmintic that increases cell membrane permeability in susceptible worms, resulting in loss of intracellular calcium, massive contractions, and paralysis of musculature. This is followed by attachment of phagocytes to parasites and death. Available as 600-mg coated tablet and is well absorbed from the GI tract.

Niclosamide (Niclocide)

Narrow-spectrum anthelmintic poorly absorbed when administered PO. Available as a 500-mg chewable tablet that must be thoroughly chewed to obtain maximal effect.

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