Intestinal Pseudo-Obstruction Questions & Answers

Updated: Jul 23, 2018
  • Author: Burt Cagir, MD, FACS; Chief Editor: John Geibel, MD, MSc, DSc, AGAF  more...
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Questions & Answers

Overview

What is intestinal pseudo-obstruction?

What is the anatomy relevant to intestinal pseudo-obstruction?

What is the pathophysiology of acute colonic pseudo-obstruction (ACPO)?

What is the pathophysiology of chronic intestinal pseudo-obstruction (CIPO)?

What causes intestinal pseudo-obstruction?

Which conditions are associated with intestinal pseudo-obstruction?

What is the prevalence of intestinal pseudo-obstruction in the US?

What is the global prevalence of intestinal pseudo-obstruction?

Which age groups have the highest prevalence of intestinal pseudo-obstruction?

What are the racial and sexual predilections of intestinal pseudo-obstruction?

What is the prognosis of intestinal pseudo-obstruction?

Presentation

Which clinical history findings are characteristic of intestinal pseudo-obstruction?

What are the signs and symptoms of intestinal pseudo-obstruction?

Which physical findings are characteristic of intestinal pseudo-obstruction?

DDX

Which conditions should be included in the differential diagnoses of intestinal pseudo-obstruction?

What are the differential diagnoses for Intestinal Pseudo-Obstruction?

Workup

Which studies are included in the workup of intestinal pseudo-obstruction?

What is the role of lab testing in the workup of intestinal pseudo-obstruction?

What is the role of plain radiography in the workup of intestinal pseudo-obstruction?

How is intestinal pseudo-obstruction differentiated from mechanical obstruction?

What is the role of contrast enema in the workup of intestinal pseudo-obstruction?

What is the role of colonoscopy in the workup of intestinal pseudo-obstruction?

Treatment

How is mechanical bowel obstruction excluded prior to treatment of intestinal pseudo-obstruction?

How is intestinal pseudo-obstruction treated?

What is included in conservative management for treatment of intestinal pseudo-obstruction?

What is the efficacy of conservative management for treatment of intestinal pseudo-obstruction?

How are constipation and obstipation prevented in intestinal pseudo-obstruction?

Which therapies should be considered for intestinal pseudo-obstruction if there is no improvement with conservative management?

What is the role of pharmacologic therapy in the treatment of intestinal pseudo-obstruction?

What is the efficacy of colonoscopy as a first- treatment of intestinal pseudo-obstruction?

What are possible adverse effects of neostigmine for treatment of intestinal pseudo-obstruction?

What are possible benefits of neostigmine for the treatment of intestinal pseudo-obstruction?

What are the contraindications to neostigmine therapy for intestinal pseudo-obstruction?

What is the efficacy of pharmacologic therapy in the treatment of intestinal pseudo-obstruction?

What is the role of colonoscopic decompression in the treatment of intestinal pseudo-obstruction?

What is the efficacy of colonoscopic decompression for the treatment of intestinal pseudo-obstruction?

What is the efficacy of diatrizoate meglumine enema for the treatment of intestinal pseudo-obstruction?

What is the efficacy of polyethylene glycol (PEG) for the treatment of intestinal pseudo-obstruction?

What is the role of surgery in the treatment of intestinal pseudo-obstruction?

What are studies regarding the efficacy of surgical intervention for treatment of intestinal pseudo-obstruction?

What is the role of fluid resuscitation in the surgical treatment of intestinal pseudo-obstruction?

How is abdominal compartment syndrome prevented in intestinal pseudo-obstruction?

What is included in the postoperative care following surgery for intestinal pseudo-obstruction?

What are the possible complications of intestinal pseudo-obstruction surgery?

Medications

Which medications are used in the treatment of intestinal pseudo-obstruction?

Which medications in the drug class Laxatives, Osmotic are used in the treatment of Intestinal Pseudo-Obstruction?

Which medications in the drug class Acetylcholinesterase Inhibitors are used in the treatment of Intestinal Pseudo-Obstruction?