Controlled Substance Schedules
Schedule I (CI)
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Drugs not used medically
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Not accepted as safe for use under medical supervision
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High abuse potential
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Possession and supply prohibited
Schedule II (CII)
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Accepted medical use
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High abuse potential
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May lead to severe psychological or physical dependence
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Examples include amphetamines, codeine, morphine, methamphetamines, and pentobarbital
Schedule III (CIII)
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Accepted medical use
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Less abuse potential than CII
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May lead to moderate to low physical dependence or high psychological dependence
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Examples include acetaminophen with codeine, anabolic steroids, glutethimide, methyprylon, and naloxone
Schedule IV (CIV)
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Accepted medical use
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Less abuse potential than CIII
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Limited physical and psychological dependence
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Examples include alprazolam, clonazepam, phenobarbital, and diazepam
Schedule V (CV)
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Often available without a prescription
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Less abuse potential than CIV
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May be subject to state and local regulations
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Examples include buprenorphine, Robitussin, pregabalin, and diphenoxylate