Beers Criteria: Considering Diagnoses or Conditions

Cardiovascular disease (high severity rating [H])

• Antiarrhythmic drugs (class Ia, Ic, III): Avoid as first-line agents for atrial fibrillation ^{[1, 2, 3, 4]}

• Disopyramide

• Dronedarone

• Digoxin >0.125 mg/day ^[1]

• High-sodium-content drugs

Hypertension (H)

• Phenylpropanolamine hydrochloride

• Pseudoephedrine

• Diet pills

• Amphetamines

Gastric/duodenal ulcer disease (H)

• Nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, aspirin >325 mg, diclofenac, etodolac, ibuprofen)

• Non–cox-2–selective NSAIDs

• Indomethacin

• Ketorolac, including parenteral

Seizures or epilepsy (H)

• Bupropion

• Clozapine

• Chlorpromazine

• Olanzapine

• Thioridazine

• Thiothixene

• Tramadol

Blood clotting disorders or anticoagulation therapy (H)

• Aspirin

• NSAIDS

• Dabigatran

• Dipyridamole

• Ticlopidine

• Clopidogrel

• Prasugrel

Bladder outflow obstruction (H)

• Anticholinergics/antispasmodic

• Oral antimuscarinics (eg, oxybutynin, darifenacin, solifenacin)

• First-generation antihistamines (eg, diphenhydramine, chlorpheniramine, cyproheptadine)

• Gastrointestinal antispasmodics

• Muscle relaxants

• Oxybutynin

• Flavoxate

• Antidepressants

• Decongestants

• Tolterodine

Stress incontinence (H)

• Alpha blockers

• Anticholinergics

• Tricyclic antidepressants

• Long-acting benzodiazepines

Arrhythmias (H)

• Tricyclic antidepressants

Insomnia (H)

• Oral decongestants

• Theophylline

• Methylphenidate

• Monoamine oxidase inhibitors (MAOIs)

• Amphetamines

Parkinson disease (H)

• Antiemetics (eg, metoclopramide, promethazine)

• Conventional antipsychotics

• Tacrine

Cognitive impairment (H)

• Barbiturates

• Anticholinergics

• Antispasmodics

• Muscle relaxants

• CNS stimulants

• H2 receptor antagonist

• Antipsychotics (as needed and long-term use)

Depression (H)

• Long-term benzodiazepines

• Sympatholytic agents

Anorexia and malnutrition (H)

• CNS stimulants

Syncope or falls (H)

• Short- to intermediate-acting benzodiazepines

• Tricyclic antidepressants

Syndrome of inappropriate antidiuretic hormone secretion/hyponatremia (low severity rating [L])

• Selective serotonin reuptake inhibitors (SSRIs)

• Carbamazepine

• Antipsychotics

Obesity (L)

• Olanzapine

Chronic obstructive pulmonary disease (H)

• Long-acting benzodiazepines

• Beta-blockers

Chronic constipation (L)

• Nondihydropyridine calcium channel blockers (eg, diltiazem and verapamil)

• Anticholinergics/antispasmodics

• Tricyclic antidepressants